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AB187906

Anti-MRPS9 antibody

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(2 Publications)

Rabbit Polyclonal MRPS9 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human MRPS9 aa 1-150.

View Alternative Names

RPMS9, MRPS9, Small ribosomal subunit protein uS9m, MRP-S9, S9mt

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS9 antibody (AB187906)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS9 antibody (AB187906)

Immunohistochemical analysis of paraffin-embedded Human colon tissue labeling MRPS9 with ab187906 at 1/200 dilution.

Immunocytochemistry/ Immunofluorescence - Anti-MRPS9 antibody (AB187906)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-MRPS9 antibody (AB187906)

Immunofluorescence analysis of A-431cells labeling MRPS9 with ab187906 at 4μg/ml.

Western blot - Anti-MRPS9 antibody (AB187906)
  • WB

Supplier Data

Western blot - Anti-MRPS9 antibody (AB187906)

All lanes:

Western blot - Anti-MRPS9 antibody (ab187906) at 1/100 dilution

Lane 1:

Human cell line RT-4 lysate

Lane 2:

Human cell line U-251MG sp lysate

Secondary

All lanes:

HRP-conjugated swine anti-rabbit immunoglobulin at 1/3000 dilution

Predicted band size: 46 kDa

true

Exposure time: 1min

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human MRPS9 aa 1-150. The exact immunogen used to generate this antibody is proprietary information.

P82933

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MRPS9 also known as mitochondrial ribosomal protein S9 is a protein involved in mitochondrial protein synthesis. Its molecular mass is approximately 43 kDa. It is expressed in the mitochondria across a variety of tissues. This protein assists in assembling the small subunit of the mitochondrial ribosome which aids in the translation of mitochondrial mRNA into functional proteins contributing to cellular energy production.
Biological function summary

MRPS9 functions as part of the mitochondrial ribosome complex specifically the 28S subunit. It plays an essential role in the process of translating mitochondrial-encoded genes which are critical for the oxidative phosphorylation pathway. MRPS9's proper function ensures the synthesis of proteins that are vital for mitochondrial function and energy production in cells.

Pathways

MRPS9 contributes significantly to the mitochondrial translation pathway which is essential for the oxidative phosphorylation system. This system is important for energy production in cells. Within the translation pathway MRPS9 interacts with other ribosomal proteins such as MRPL37 and MRPS18. These interactions facilitate the translation and synthesis of proteins important for maintaining mitochondrial function and energy homeostasis.

MRPS9 is connected to conditions involving mitochondrial dysfunctions such as mitochondrial myopathy. Such disorders often result from impaired energy production due to defective mitochondrial translation. In these conditions there are often interactions noted with proteins like MRPL44 and other components of the oxidative phosphorylation system illustrating the interconnectedness between mitochondrial ribosomal proteins and cellular energy defects.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information MRPS9
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

American journal of human genetics 112:59-74 PubMed39701103

2024

Bi-allelic variants in DAP3 result in reduced assembly of the mitoribosomal small subunit with altered apoptosis and a Perrault-syndrome-spectrum phenotype.

Applications

Unspecified application

Species

Unspecified reactive species

Thomas B Smith,Robert Kopajtich,Leigh A M Demain,Alessandro Rea,Huw B Thomas,Manuel Schiff,Christian Beetz,Shelagh Joss,Gerard S Conway,Anju Shukla,Mayuri Yeole,Periyasamy Radhakrishnan,Hatem Azzouz,Amel Ben Chehida,Monique Elmaleh-Bergès,Ruth I C Glasgow,Kyle Thompson,Monika Oláhová,Langping He,Emma M Jenkinson,Amir Jahic,Inna A Belyantseva,Melanie Barzik,Jill E Urquhart,James O'Sullivan,Simon G Williams,Sanjeev S Bhaskar,Samantha Carrera,Alexander J M Blakes,Siddharth Banka,Wyatt W Yue,Jamie M Ellingford,Henry Houlden,Kevin J Munro,Thomas B Friedman,Robert W Taylor,Holger Prokisch,Raymond T O'Keefe,William G Newman

Life science alliance 1:e201800070 PubMed30456350

2018

Proteomics and neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity.

Applications

Unspecified application

Species

Unspecified reactive species

Hannelore Hartmann,Daniel Hornburg,Mareike Czuppa,Jakob Bader,Meike Michaelsen,Daniel Farny,Thomas Arzberger,Matthias Mann,Felix Meissner,Dieter Edbauer
View all publications
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