AB255608

Anti-MS2 antibody [EPR22688-44]

RabMAb
Recombinant
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(5 Publications)

Rabbit Recombinant Monoclonal MS2 antibody. Suitable for IHC-P, ICC/IF and reacts with Mouse, Rat, Human samples. Cited in 5 publications.

View Alternative Names

CD156a, MS2, ADAM8, Disintegrin and metalloproteinase domain-containing protein 8, ADAM 8, Cell surface antigen MS2

5 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS2 antibody [EPR22688-44] (AB255608)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS2 antibody [EPR22688-44] (AB255608)

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue labeling ADAM8 with ab255608 at 1/2000 dilution followed by a ready to use Goat Anti-Rabbit IgG H&L (HRP). Positive staining in human breast cancer (PMID : 24375628, PMID : 30635388) Counterstained with Hematoxylin.

Secondary antibody only control : Secondary antibody is a ready to use Goat Anti-Rabbit IgG H&L (HRP).

Heat mediated antigen retrieval using ab93684 (Tris/EDTA buffer, pH 9.0).

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS2 antibody [EPR22688-44] (AB255608)

Immunohistochemical analysis of paraffin-embedded Human colon tissue labeling ADAM8 with ab255608 at 1/2000 dilution followed by a ready to use Goat Anti-Rabbit IgG H&L (HRP). Positive staining in immune cells of human colon (PMID : 17270707) The population of positively stained cells depends on cases. Counterstained with Hematoxylin.

Secondary antibody only control : Secondary antibody is a ready to use Goat Anti-Rabbit IgG H&L (HRP).

Heat mediated antigen retrieval using ab93684 (Tris/EDTA buffer, pH 9.0).

Immunocytochemistry/ Immunofluorescence - Anti-MS2 antibody [EPR22688-44] (AB255608)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-MS2 antibody [EPR22688-44] (AB255608)

Immunofluorescent analysis of 4% Paraformaldehyde-fixed, 0.1% TritonX-100 permeabilized 293T (human embryonic kidney epithelial cell) cells labelling ADAM8 with ab255608 at 1/100 dilution, followed by ab150077 AlexaFluor^®488 Goat anti-Rabbit secondary antibody at 1/1000 dilution (Green). Confocal image showing cytoplasmic staining in 293T cells transfected with myc-tagged ADAM8 expression vector. ab195889 Anti-alpha Tubulin antibody [DM1A] - Microtubule Marker (Alexa Fluor^® 594) was used to counterstain tubulin at 1/200 dilution (Red). The Nuclear counterstain was DAPI (Blue).

Secondary antibody only control : Secondary antibody is ab150077 AlexaFluor®488 Goat anti-Rabbit secondary at 1/1000 dilution.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS2 antibody [EPR22688-44] (AB255608)

Immunohistochemical analysis of paraffin-embedded Mouse colon tissue labeling ADAM8 with ab255608 at 1/2000 dilution followed by a ready to use Goat Anti-Rabbit IgG H&L (HRP). Positive staining in immune cells of mouse colon (PMID : 17270707) Counterstained with Hematoxylin.

Secondary antibody only control : Secondary antibody is a ready to use Goat Anti-Rabbit IgG H&L (HRP).

Heat mediated antigen retrieval using ab93684 (Tris/EDTA buffer, pH 9.0).

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS2 antibody [EPR22688-44] (AB255608)

Immunohistochemical analysis of paraffin-embedded Rat colon tissue labeling ADAM8 with ab255608 at 1/2000 dilution followed by a ready to use Goat Anti-Rabbit IgG H&L (HRP). Positive staining in immune cells of rat colon (PMID : 17270707) Counterstained with Hematoxylin.

Secondary antibody only control : Secondary antibody is a ready to use Goat Anti-Rabbit IgG H&L (HRP).

Heat mediated antigen retrieval using ab93684 (Tris/EDTA buffer, pH 9.0).

Carrier free

Anti-MS2 antibody [EPR22688-44] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR22688-44

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

ICC/IF, IHC-P

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/2000", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100", "ICCIF-species-notes": "" }, "Mouse": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/2000", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/2000", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.5% BSA

Shipped at conditions

Conditional Ambient

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Possible involvement in extravasation of leukocytes.

See full target information ADAM8

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Signal transduction and targeted therapy 10:299 PubMed40935839

2025

Coinhibition of the MEK/RTK pathway has high therapeutic efficacy in KRAS-mutant non-small cell lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jun Lu,Minjuan Hu,Yikai Zhao,Tianqing Chu,Wei Zhang,Yijia Zhou,Xinlei Cai,Jun Wu,Liang Hu,Chunlei Shi,Liwen Xiong,Aiqin Gu,Huimin Wang,Yanwei Zhang,Yuqing Lou,Runbo Zhong,Zhiqiang Gao,Hongyu Liu,Chao Zhou,Yingli Wu,Liang Zhu,Hua Zhong,Hongbin Ji,Baohui Han

Medicine 104:e41375 PubMed39889162

2025

Potential prognostic and immunologic significances of ADAM8 in clear cell renal cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Ming Chuan Chu,Zhi Lei Zhang,Zhi Qiang Wang,Zong Yang Li,Yong Shun Guo

Nature communications 13:945 PubMed35177618

2022

Stroke induces disease-specific myeloid cells in the brain parenchyma and pia.

Applications

Unspecified application

Species

Unspecified reactive species

Carolin Beuker,David Schafflick,Jan-Kolja Strecker,Michael Heming,Xiaolin Li,Jolien Wolbert,Antje Schmidt-Pogoda,Christian Thomas,Tanja Kuhlmann,Irene Aranda-Pardos,Noelia A-Gonzalez,Praveen Ashok Kumar,Yves Werner,Ertugrul Kilic,Dirk M Hermann,Heinz Wiendl,Ralf Stumm,Gerd Meyer Zu Hörste,Jens Minnerup

Oncology reports 46: PubMed34617574

2021

Propofol mediates pancreatic cancer cell activity through the repression of ADAM8 via SP1.

Applications

Unspecified application

Species

Unspecified reactive species

Yutong Gao,Yu Zhou,Chunlin Wang,Klarke M Sample,Xiangdi Yu,Yaacov Ben-David

Adipocyte 10:131-141 PubMed33648423

2021

Effects of non-vascularized adipose tissue transplantation on its genetic profile.

Applications

Unspecified application

Species

Unspecified reactive species

Jeannine S Schreiter,L O Kurow,S Langer,M Steinert,L Massier

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-MS2 antibody [EPR22688-44]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS2 antibody [EPR22688-44] (AB255608)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS2 antibody [EPR22688-44] (AB255608)

Immunocytochemistry/ Immunofluorescence - Anti-MS2 antibody [EPR22688-44] (AB255608)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS2 antibody [EPR22688-44] (AB255608)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS2 antibody [EPR22688-44] (AB255608)

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Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (5)

Product promise