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AB188257

Anti-MS4A10 antibody - N-terminal

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(1 Publication)

Rabbit Polyclonal MS4A10 antibody. N-terminal. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MS4A10 aa 1-100.

View Alternative Names

CD20L7, MS4A9, MS4A10, Membrane-spanning 4-domains subfamily A member 10, CD20 antigen-like 7

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS4A10 antibody - N-terminal (AB188257)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS4A10 antibody - N-terminal (AB188257)

Immunohistochemical analysis of paraffin embedded Human corpus uterine tissue labeling MS4A10 with ab188257 at 1/200 dilution

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human MS4A10 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q96PG2

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MS4A10 also known as Membrane-Spanning 4-Domains Subfamily A Member 10 is a membrane protein with a molecular mass of approximately 25 kDa. It belongs to the MS4A family characterized by four transmembrane domains. MS4A10 is mainly expressed in fetal tissues but shows notable expression in adult tissues like the colon and small intestine. The protein is localized in the cellular membrane implying its potential role in signal transduction processes within these tissues.
Biological function summary

This protein participates in cellular signaling and communication influencing immune responses. While it is not reported as a part of a major protein complex MS4A10 associates closely with other MS4A family members. These interactions suggest involvement in modulating immune cell functions perhaps by mediating cell surface signaling pathways or acting as a receptor or co-receptor on specific immune cells.

Pathways

MS4A10 links to the cell signaling pathways involved in immune response regulation. It shows associations with signaling pathways such as the MAPK pathway and the JAK-STAT pathway. These pathways play significant roles in cell proliferation differentiation and apoptosis. MS4A10 may interact with related proteins such as other MS4A family members within these pathways affecting the signal transduction mechanisms they govern.

Significant alterations or dysregulation of MS4A10 expression have associations with colorectal cancer and inflammatory bowel disease (IBD). In colorectal cancer MS4A10 possibly interacts with other proteins such as MS4A1 suggesting a role in tumorigenesis or cancer cell survival. In IBD alterations in MS4A10 expression might affect immune processes linking it to proteins that modulate inflammation contributing to disease pathology.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in signal transduction as a component of a multimeric receptor complex.
See full target information MS4A10
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Genes & development 14:2757-70 PubMed11069892

2000

Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.

Applications

Unspecified application

Species

Unspecified reactive species

T Tomonaga,K Nagao,Y Kawasaki,K Furuya,A Murakami,J Morishita,T Yuasa,T Sutani,S E Kearsey,F Uhlmann,K Nasmyth,M Yanagida
View all publications
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