JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB182151

Anti-MS4A14 antibody [EPR14020]

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Recombinant Monoclonal MS4A14 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

MS4A13, MS4A16, MS4A14, Membrane-spanning 4-domains subfamily A member 14, Testis development protein NYD-SP21

2 Images
Western blot - Anti-MS4A14 antibody [EPR14020] (AB182151)
  • WB

Supplier Data

Western blot - Anti-MS4A14 antibody [EPR14020] (AB182151)

All lanes:

Western blot - Anti-MS4A14 antibody [EPR14020] (ab182151) at 1/20000 dilution

Lane 1:

Human thymus lysate at 10 µg

Lane 2:

Human testis lysate at 10 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab136636'>ab136636</a>) at 1/500 dilution

Predicted band size: 122 kDa,77 kDa

false

Western blot - Anti-MS4A14 antibody [EPR14020] (AB182151)
  • WB

Supplier Data

Western blot - Anti-MS4A14 antibody [EPR14020] (AB182151)

All lanes:

Western blot - Anti-MS4A14 antibody [EPR14020] (ab182151) at 1/20000 dilution

Lane 1:

THP1 cell lysate at 20 µg

Lane 2:

MCF7 cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 77 kDa

false

  • Carrier free

    Anti-MS4A14 antibody [EPR14020] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR14020

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/10000 - 1/50000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
style
left-column

Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

style
left-column

Properties and storage information

Form
Liquid
Purity
Tissue culture supernatant
Storage buffer
pH: 7.2 Preservative: 0.01% Sodium azide Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MS4A14 also known by its alternate names is part of the membrane-spanning 4-domains subfamily A. It has a molecular mass of approximately 54 kDa. This protein usually expresses in specific tissues such as the brain and testes. MS4A14 has a structure characterized by four transmembrane domains which indicates its role in cellular communication and membrane signaling processes.
Biological function summary

This protein participates in modulating signal transduction across the cellular membrane. MS4A14 associates with lipid rafts which facilitates its role in signaling events. It does not operate alone but as part of larger protein complexes interacting with other proteins to carry out its function. The precise complexes it forms are under continued research seeking to clarify its biological roles fully.

Pathways

This protein integrates within certain cellular signaling cascades. One important pathway it involves is the calcium-mediated signaling pathway. MS4A14 interacts with various proteins within this pathway such as calcium channels to help regulate ion flow across membranes. Another related pathway is immune response modulation though its exact partners in these cascades require further investigation to fully understand its integrative roles.

MS4A14 has links to Alzheimer's disease and certain forms of cancer. In Alzheimer's it interacts with proteins involved in amyloid-beta processing which plays an important role in disease progression. Its relation to cancer seems to connect to pathways influencing cell proliferation and apoptosis but the exact mechanisms and associated proteins are still subjects of active research. Understanding these connections could inform potential therapeutic targets.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

May be involved in signal transduction as a component of a multimeric receptor complex.
See full target information MS4A14
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in immunology 13:853088 PubMed35651604

2022

Development of a Phagocytosis-Dependent Gene Signature to Predict Prognosis and Response to Checkpoint Inhibition in Clear-Cell Renal Cell Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Kunping Li,Yuqing Li,Yinfeng Lyu,Linyi Tan,Xinyi Zheng,Haowen Jiang,Hui Wen,Chenchen Feng
View all publications
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB76149

Anti-YB1 antibody [EP2708Y]

RabMAb|Recombinant

Western blot - Anti-YB1 antibody [EP2708Y] (AB76149)

  • 5
  • 3
Primary Antibodies

AB108931

Anti-HAUSP / USP7 antibody [EPR4253]

RabMAb|Recombinant|KO Validated

Western blot - Anti-HAUSP / USP7 antibody [EPR4253] (AB108931)

  • 4
  • 2
Proteins & Peptides

AB289753

Recombinant Human ADTRP protein

SDS-PAGE - Recombinant Human ADTRP protein (AB289753)

  • 0
  • 0
Primary Antibodies

AB181869

Anti-VAMP2 antibody [EPR12790]

RabMAb|Recombinant

Western blot - Anti-VAMP2 antibody [EPR12790] (AB181869)

  • 5
  • 1

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com