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AB96174

Anti-MSTO1 antibody

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(2 Publications)

Rabbit Polyclonal MSTO1 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human MSTO1 aa 1-300.

View Alternative Names

LST005, SLTP005, MSTO1, Protein misato homolog 1

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MSTO1 antibody (AB96174)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MSTO1 antibody (AB96174)

Immunohistochemical analysis of paraffin-embedded OVCA xenograft, using ab96174 at 1/100 dilution.

Antigen Retrieval : Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Western blot - Anti-MSTO1 antibody (AB96174)
  • WB

Supplier Data

Western blot - Anti-MSTO1 antibody (AB96174)

Samples were separated by 7.5% SDS-PAGE.

All lanes:

Western blot - Anti-MSTO1 antibody (ab96174) at 1/1000 dilution

Lane 1:

A549 whole cell lysates at 30 µg

Lane 2:

H1299 whole cell lysates at 30 µg

Lane 3:

HCT116 whole cell lysates at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 62 kDa

false

Western blot - Anti-MSTO1 antibody (AB96174)
  • WB

Supplier Data

Western blot - Anti-MSTO1 antibody (AB96174)

Samples were separated by 7.5% SDS-PAGE.

All lanes:

Western blot - Anti-MSTO1 antibody (ab96174) at 1/1000 dilution

Lane 1:

A431 whole cell lysates at 30 µg

Lane 2:

HeLa whole cell lysates at 30 µg

Lane 3:

HepG2 whole cell lysates at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 62 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human MSTO1 aa 1-300. The exact immunogen used to generate this antibody is proprietary information.

Q9BUK6

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MSTO1 also known as Misato homolog 1 is an important protein involved in mitochondrial dynamics. It weighs approximately 64 kDa. MSTO1 is expressed in several tissues with higher levels in skeletal muscle heart and liver. This protein plays an active role in the regulation of mitochondrial morphology by promoting mitochondrial fission and movement within cells.
Biological function summary

MSTO1 influences cellular energy management and influences mitochondrial distribution. It does not form a consistent complex but interacts with other mitochondrial-associated proteins to maintain mitochondrial function. Proper functioning of MSTO1 ensures effective energy supply and cellular respiration which are essential for high-energy-demand tissues.

Pathways

MSTO1 interacts in the mitochondrial fission and fusion pathways essential for maintaining mitochondrial integrity and function. This protein works alongside other key proteins such as Drp1 and OPA1 to regulate the balance between mitochondrial division and fusion which is necessary for cellular health and homeostasis.

MSTO1 mutations or dysfunctions have been linked to neurodegenerative disorders and myopathy. People with alterations in MSTO1 may experience symptoms of mitochondrial disorders such as muscle weakness or neurodegeneration. Additionally MSTO1's relationship with proteins like Drp1 suggests a pathway connection where dysregulation could contribute to conditions like Charcot-Marie-Tooth disease emphasizing its potential role in mitochondrial-related diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Involved in the regulation of mitochondrial distribution and morphology (PubMed : 17349998, PubMed : 28544275, PubMed : 28554942). Required for mitochondrial fusion and mitochondrial network formation (PubMed : 28544275, PubMed : 28554942).
See full target information MSTO1
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Journal of cellular and molecular medicine 26:1656-1671 PubMed35092120

2022

CTNNAL1 participates in the regulation of mucus overproduction in HDM-induced asthma mouse model through the YAP-ROCK2 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Di Wu,Wang Jiang,Caixia Liu,Lexin Liu,Furong Li,Xiaodi Ma,Lang Pan,Chi Liu,Xiangping Qu,Huijun Liu,Xiaoqun Qin,Yang Xiang

Computational and mathematical methods in medicine 2021:6468405 PubMed34812269

2021

Inhibition of miR-15a-5p Promotes the Chemoresistance to Pirarubicin in Hepatocellular Carcinoma via Targeting eIF4E.

Applications

Unspecified application

Species

Unspecified reactive species

Ying Zhang,Qingsong Tie,Zhiwei Bao,Zhi Shao,Lan Zhang
View all publications
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Product promise

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