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AB198217

Anti-MTP18 antibody

4

(2 Reviews)

|

(8 Publications)

Rabbit Polyclonal MTP18 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 8 publications. Immunogen corresponding to Recombinant Fragment Protein within Human MTFP1.

View Alternative Names

MTP18, HSPC242, My022, MTFP1, Mitochondrial fission process protein 1, Mitochondrial 18 kDa protein

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MTP18 antibody (AB198217)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MTP18 antibody (AB198217)

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling MTP18 with ab198217 at 1/30 dilution.

Western blot - Anti-MTP18 antibody (AB198217)
  • WB

Supplier Data

Western blot - Anti-MTP18 antibody (AB198217)

10% SDS-PAGE.

All lanes:

Western blot - Anti-MTP18 antibody (ab198217) at 1/450 dilution

Lane 1:

Mouse heart tissue lysate at 40 µg

Lane 2:

Mouse muscle tissue lysate at 40 µg

Lane 3:

HeLa cell lysate at 40 µg

Lane 4:

Mouse liver tissue lysate at 40 µg

Lane 5:

Mouse kidney tissue lysate at 40 µg

Lane 6:

HepG2 cell lysate at 40 µg

Predicted band size: 18 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human MTFP1. The exact immunogen used to generate this antibody is proprietary information.

Q9UDX5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function induces the release of cytochrome c, which activates the caspase cascade and leads to apoptosis.
See full target information MTFP1
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Publications (8)

Recent publications for all applications. Explore the full list and refine your search

iScience 26:106045 PubMed36818298

2023

NRF3 activates mTORC1 arginine-dependently for cancer cell viability.

Applications

Unspecified application

Species

Unspecified reactive species

Shuuhei Hirose,Tsuyoshi Waku,Misato Tani,Haruka Masuda,Keiko Endo,Sanae Ashitani,Iori Aketa,Hina Kitano,Sota Nakada,Ayaka Wada,Atsushi Hatanaka,Tsuyoshi Osawa,Tomoyoshi Soga,Akira Kobayashi

Journal of Alzheimer's disease : JAD 91:1323-1338 PubMed36617782

2023

Early Mitochondrial Defects in the 5xFAD Mouse Model of Alzheimer's Disease.

Applications

Unspecified application

Species

Unspecified reactive species

Neelam Sharma,Rupkatha Banerjee,Ronald L Davis

Nature communications 12:4980 PubMed34404792

2021

Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery.

Applications

Unspecified application

Species

Unspecified reactive species

Wei Qin,Samuel A Myers,Dominique K Carey,Steven A Carr,Alice Y Ting

Molecules and cells 42:893-905 PubMed31822044

2019

Augmenter of Liver Regeneration Alleviates Renal Hypoxia-Reoxygenation Injury by Regulating Mitochondrial Dynamics in Renal Tubular Epithelial Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Rui-Ting Long,Jun-Bo Peng,Li-Li Huang,Gui-Ping Jiang,Yue-Juan Liao,Hang Sun,Yu-Dong Hu,Xiao-Hui Liao

Scientific reports 9:10669 PubMed31337818

2019

MTP18 is a Novel Regulator of Mitochondrial Fission in CNS Neuron Development, Axonal Growth, and Injury Responses.

Applications

Unspecified application

Species

Unspecified reactive species

Alexander Kreymerman,David N Buickians,Michael M Nahmou,Tammy Tran,Joana Galvao,Yan Wang,Nicholas Sun,Leah Bazik,Star K Huynh,In-Jae Cho,Tomasz Boczek,Kun-Che Chang,Noelia J Kunzevitzky,Jeffrey L Goldberg

The Journal of clinical investigation 128:5448-5464 PubMed30325740

2018

MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury.

Applications

Unspecified application

Species

Unspecified reactive species

Qingqing Wei,Haipeng Sun,Shuwei Song,Yong Liu,Pengyuan Liu,Man Jiang Livingston,Jianwen Wang,Mingyu Liang,Qing-Sheng Mi,Yuqing Huo,Norris Stanley Nahman,Changlin Mei,Zheng Dong

Molecular cell 67:922-935.e5 PubMed28918902

2017

mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1.

Applications

Unspecified application

Species

Unspecified reactive species

Masahiro Morita,Julien Prudent,Kaustuv Basu,Vanessa Goyon,Sakie Katsumura,Laura Hulea,Dana Pearl,Nadeem Siddiqui,Stefan Strack,Shawn McGuirk,Julie St-Pierre,Ola Larsson,Ivan Topisirovic,Hojatollah Vali,Heidi M McBride,John J Bergeron,Nahum Sonenberg

Oncotarget 8:56582-56597 PubMed28915614

2017

Mitochondrial protein 18 (MTP18) plays a pro-apoptotic role in chemotherapy-induced gastric cancer cell apoptosis.

Applications

WB

Species

Unspecified reactive species

Lynn H H Aung,Ruibei Li,Bellur S Prabhakar,Ajay V Maker,Peifeng Li
View all publications
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Product promise

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