AB136615

Anti-MUC1 antibody [G22-L]

Name: Anti-MUC1 antibody [G22-L] (ab136615) | Abcam
Brand: Abcam Limited
SKU: AB136615
Price: 545 USD
Availability: InStock

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(2 Publications)

Rabbit Monoclonal MUC1 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human MUC1.

View Alternative Names

CD227, PUM, MUC1, Mucin-1, MUC-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, Carcinoma-associated mucin, Episialin, H23AG, Krebs von den Lungen-6, PEMT, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin, CA 15-3, KL-6, PEM, EMA

3 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC1 antibody [G22-L] (AB136615)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC1 antibody [G22-L] (AB136615)

Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human stomach tissue labelling MUC1 with ab136615 antibody at a dilution of 1/100.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC1 antibody [G22-L] (AB136615)

Immunohistochemical analysis of formalin/paraffin embedded human sebaceous glands of the skin tissue labeling MUC1 with ab136615.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC1 antibody [G22-L] (AB136615)

Immunohistochemical analysis of formalin/paraffin embedded human pulmonary adenocarcinoma tissue labeling MUC1 with ab136615.

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

G22-L

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human MUC1. The exact immunogen used to generate this antibody is proprietary information.

P15941

Epitope

Antibody recognizes the epitope located between Gly1235 - Ala1253

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." } } }

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Properties and storage information

Form

Liquid

Purification notes

This immunoglobulin is the product of one single B-cell line from the crude anti-peptide polyclonal anti-serum. This antibody is purified using a propriety technique and offers a completely post-translationally modified and properly glycosylated antibody. This offers increased stability.

Storage buffer

pH: 8 Preservative: 0.05% Sodium azide Constituents: 2% BSA, 0.32% Tris HCl

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

See full target information MUC1

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Cancers 11: PubMed30991738

2019

Identification of KIF11 As a Novel Target in Meningioma.

Applications

Unspecified application

Species

Unspecified reactive species

Gerhard Jungwirth,Tao Yu,Mahmoud Moustafa,Carmen Rapp,Rolf Warta,Christine Jungk,Felix Sahm,Steffen Dettling,Klaus Zweckberger,Katrin Lamszus,Christian Senft,Mario Loehr,Almuth F Keßler,Ralf Ketter,Manfred Westphal,Juergen Debus,Andreas von Deimling,Matthias Simon,Andreas Unterberg,Amir Abdollahi,Christel Herold-Mende

Oncology letters 11:4113-4116 PubMed27313750

2016

An unusual mediastinal parathyroid carcinoma coproducing PTH and PTHrP: A case report.

Applications

Unspecified application

Species

Unspecified reactive species

Chuangjie Cao,Chengyun Dou,Fuqin Chen,Yan Wang,Xiaoli Zhang,Hong Lai

View all publications

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