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AB150381

Anti-MUC4 antibody [EPR9308]

3

(2 Reviews)

|

(5 Publications)

Rabbit Recombinant Monoclonal MUC4 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 5 publications.

View Alternative Names

Mucin-4, MUC-4, Ascites sialoglycoprotein, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucin, ASGP, MUC4

5 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)

Immunohistochemical analysis of paraffin embedded Human colon tissue labeling MUC4 with unpurified ab150381 at a 1/50 dilution.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon tissue sections labeling MUC4 with purified ab150381 at 1 : 750 dilution (1.44 μg/ml). Heat mediated antigen retrieval was performed using ab93684 (Tris/EDTA buffer, pH 9.0). Tissue was counterstained with hematoxylin. ImmunoHistoProbe one step HRP Polymer (ready to use) secondary antibody was used. PBS instead of the primary antibody was used as the negative control.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)

Immunohistochemical analysis of paraffin embedded Human Stomach adenocarcinoma tissue using unpurified ab150381 showing -ve staining.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)

Immunohistochemical analysis of paraffin embedded Human Pancreatic carcinoma tissue using unpurified ab150381 showing +ve staining.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)

Immunohistochemical analysis of paraffin embedded normal Human pancreas tissue using unpurified ab150381 showing -ve staining.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

  • Carrier free

    Anti-MUC4 antibody [EPR9308] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR9308

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/750", "IHCP-species-notes": "<p><strong>For unpurified use at 1:50 - 1:100. </strong></p>" } } }
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Product details

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Membrane-bound mucin, a family of highly glycosylated proteins that constitute the major component of the mucus, the slimy and viscous secretion covering epithelial surfaces (PubMed : 10880978). These glycoproteins play important roles in the protection of the epithelium and are implicated in epithelial renewal and differentiation (PubMed : 10880978). Regulates cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and its ability to act as an intramembrane ligand for ERBB2. Plays an important role in proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. In polarized epithelial cells, segregates ERBB2 and other ERBB receptors and prevents ERBB2 from acting as a coreceptor. The interaction with ERBB2 leads to enhanced expression of CDKN1B. The formation of a MUC4-ERBB2-ERBB3-NRG1 complex leads to down-regulation of CDKN1B, resulting in repression of apoptosis and stimulation of proliferation. Its ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation.
See full target information MUC4
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Cell reports. Medicine 6:101990 PubMed40054460

2025

Self-assembled patient-derived tumor-like cell clusters for personalized drug testing in diverse sarcomas.

Applications

Unspecified application

Species

Unspecified reactive species

Tian Gao,Xinyu He,Junyi Wang,Jiayong Liu,Xiongbing Hu,Chujie Bai,Shenyi Yin,Yunfei Shi,Yanmin Wang,Zhichao Tan,Fang Cao,Shu Li,Yan-Jie Shi,Ruifeng Xue,Juan Li,Yang He,Jiaxin Li,Huinan Lu,Hanshuo Zhang,Lu Zhang,Zhiwei Fang,Xinyu Wang,Mengmeng Liu,Wenjun Fu,Lei Tang,Buqing Ye,Zhengfu Fan,Jianzhong Jeff Xi

Nature genetics 55:2175-2188 PubMed37985817

2023

Multiomic analysis of cervical squamous cell carcinoma identifies cellular ecosystems with biological and clinical relevance.

Applications

Unspecified application

Species

Unspecified reactive species

Junpeng Fan,Funian Lu,Tianyu Qin,Wenju Peng,Xucui Zhuang,Yinuo Li,Xin Hou,Zixuan Fang,Yunyi Yang,Ensong Guo,Bin Yang,Xi Li,Yu Fu,Xiaoyan Kang,Zimeng Wu,Lili Han,Gordon B Mills,Xiangyi Ma,Kezhen Li,Peng Wu,Ding Ma,Gang Chen,Chaoyang Sun

Journal of nanobiotechnology 21:79 PubMed36882792

2023

Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation.

Applications

Unspecified application

Species

Unspecified reactive species

Linjun Hong,Xupeng Zang,Qun Hu,Yanjuan He,Zhiqian Xu,Yanshe Xie,Ting Gu,Huaqiang Yang,Jie Yang,Junsong Shi,Enqin Zheng,Sixiu Huang,Zheng Xu,Dewu Liu,Gengyuan Cai,Zicong Li,Zhenfang Wu

Heliyon 5:e02753 PubMed31844699

2019

Assessing the prognostic significance of MUC4β in mucoepidermoid carcinoma of the salivary glands: An immunohistochemical study.

Applications

Unspecified application

Species

Unspecified reactive species

Poonam R Sawant,Anita Spadigam,Anita Dhupar,Shaheen Syed,Karla Carvalho

Oncotarget 7:39332-39344 PubMed27322428

2016

Analysis of the correlation between lipotoxicity and pituitary-thyroid axis hormone levels in men and male rats.

Applications

Unspecified application

Species

Unspecified reactive species

Jianmei Yang,Xiaoming Zhou,Xu Zhang,Jianting Hu,Ling Gao,Yongfeng Song,Chunxiao Yu,Shanshan Shao,Zhongshang Yuan,Yan Sun,Huili Yan,Guimei Li,Jiajun Zhao
View all publications
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Product promise

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