AB105460

Anti-MUC5B antibody [6F10-E4]

Name: Anti-MUC5B antibody [6F10-E4] (ab105460) | Abcam
Brand: Abcam Limited
SKU: AB105460
Price: 410 USD
Availability: InStock

Be the first to review this product! Submit a review

(7 Publications)

Anti-MUC5B antibody [6F10-E4] (ab105460) is a mouse monoclonal antibody detecting MUC5B in Western Blot, ELISA. Suitable for Human.

View Alternative Names

MUC5, MUC5B, Mucin-5B, MUC-5B, Cervical mucin, High molecular weight salivary mucin MG1, Sublingual gland mucin

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

6F10-E4

Isotype

IgG1

Light chain type

kappa

Carrier free

Reacts with

Human

Applications

ELISA, WB

applications

Immunogen

Synthetic Peptide within Human MUC5B conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q9HC84

Specificity

Non glycosylated domain of mucin MUC5B.

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>Please consult PubMed ID 14678646 for the recommended electrophoresis conditions.</p>" } } }

style

left-column

Product details

What is this antibody validated in?
Anti-MUC5B antibody [6F10-E4] (ab105460) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), ELISA in Human samples.

What is the molecular weight of MUC5B?
Anti-MUC5B [6F10-E4] (ab105460) specifically detects a band for MUC5B (UniProt: Q9HC84) at a molecular weight of 596kDa.

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

Preservative: 0.02% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus.

See full target information MUC5B

style

left-column

Publications (7)

Recent publications for all applications. Explore the full list and refine your search

Glycobiology 34: PubMed39173029

2024

Sialylated keratan sulfates on MUC5B are Siglec-8 ligands in the human esophagus.

Applications

Unspecified application

Species

Unspecified reactive species

T August Li,Anabel Gonzalez-Gil,Abduselam K Awol,Steven J Ackerman,Benjamin C Orsburn,Ronald L Schnaar

Molecules (Basel, Switzerland) 27: PubMed35807530

2022

High Expression Level of α2-3-Linked Sialic Acids on Salivary Glycoproteins of Breastfeeding Women May Help to Protect Them from Avian Influenza Virus Infection.

Applications

Unspecified application

Species

Unspecified reactive species

Li Ding,Yimin Cheng,Wei Guo,Siyue Sun,Xiangqin Chen,Tiantian Zhang,Hongwei Cheng,Jiayue Hao,Yunhua Lu,Xiurong Wang,Zheng Li

Cell reports 33:108402 PubMed33207190

2020

Functional Specialization of Human Salivary Glands and Origins of Proteins Intrinsic to Human Saliva.

Applications

Unspecified application

Species

Unspecified reactive species

Marie Saitou,Eliza A Gaylord,Erica Xu,Alison J May,Lubov Neznanova,Sara Nathan,Anissa Grawe,Jolie Chang,William Ryan,Stefan Ruhl,Sarah M Knox,Omer Gokcumen

Frontiers in cellular and infection microbiology 10:557273 PubMed33224896

2020

Characterization of Oral Immunity in Cases and Close Household Contacts Exposed to Andes Orthohantavirus (ANDV).

Applications

Unspecified application

Species

Unspecified reactive species

Constanza Martinez-Valdebenito,Camila Andaur,Jenniffer Angulo,Carolina Henriquez,Marcela Ferrés,Nicole Le Corre

Oral diseases 24:972-982 PubMed29637662

2018

Early salivary changes in multiple myeloma patients undergoing autologous HSCT.

Applications

Unspecified application

Species

Unspecified reactive species

Sjm van Leeuwen,G B Proctor,Cmj Potting,S Ten Hoopen,Lfj van Groningen,E M Bronkhorst,Nma Blijlevens,McDnjm Huysmans

American journal of respiratory and critical care medicine 194:1296-1299 PubMed27845589

2016

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

Applications

Unspecified application

Species

Unspecified reactive species

Marrah E Lachowicz-Scroggins,Shaopeng Yuan,Sheena C Kerr,Eleanor M Dunican,Michelle Yu,Stephen D Carrington,John V Fahy

Hybridoma and hybridomics 22:293-9 PubMed14678646

2003

New monoclonal antibodies to non-glycosylated domains of the secreted mucins MUC5B and MUC7.

Applications

WB, ELISA

Species

Human, Human

K Rousseau,C Wickstrom,D B Whitehouse,I Carlstedt,D M Swallow

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-MUC5B antibody [6F10-E4]

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Carrier free

Reacts with

Applications

Immunogen

Specificity

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (7)

Alternative Products

Primary Antibodies

Primary Antibodies

Complementary Products

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Product promise