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AB121647

Anti-MURC antibody

4

(2 Reviews)

|

(3 Publications)

Rabbit Polyclonal MURC antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CAVIN4 aa 50-200.

View Alternative Names

MURC, CAVIN4, Caveolae-associated protein 4, Muscle-related coiled-coil protein, Muscle-restricted coiled-coil protein

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-MURC antibody (AB121647)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-MURC antibody (AB121647)

Immunofluorescent staining of Human cell line U-2 OS shows positivity in plasma membrane and cytoskeleton (microtubules). Recommended concentration of ab121647 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MURC antibody (AB121647)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MURC antibody (AB121647)

ab121647, at 1/1000 dilution, staining MURC in paraffin-embedded Human skeletal muscle tissue, by Immunohistochemistry.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human CAVIN4 aa 50-200. The exact immunogen used to generate this antibody is proprietary information.

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Alternative Products

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AB121642

Anti-MURC antibody

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1-4 µg/mL", "ICCIF-species-notes": "<p>Recommend PFA Fixation and Triton X-100 treatment</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Modulates the morphology of formed caveolae in cardiomyocytes, but is not required for caveolar formation. Facilitates the recruitment of MAPK1/3 to caveolae within cardiomyocytes and regulates alpha-1 adrenergic receptor-induced hypertrophic responses in cardiomyocytes through MAPK1/3 activation. Contributes to proper membrane localization and stabilization of caveolin-3 (CAV3) in cardiomyocytes (By similarity). Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway (PubMed : 18332105).
See full target information CAVIN4
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 15:6141 PubMed39034316

2024

Systemic delivery of full-length dystrophin in Duchenne muscular dystrophy mice.

Applications

Unspecified application

Species

Unspecified reactive species

Yuan Zhou,Chen Zhang,Weidong Xiao,Roland W Herzog,Renzhi Han

International journal of molecular sciences 22: PubMed34502507

2021

Regulation of the Golgi Apparatus by p38 and JNK Kinases during Cellular Stress Responses.

Applications

Unspecified application

Species

Unspecified reactive species

Cathrine Nordgaard,Maxim A X Tollenaere,Ana Martinez Del Val,Dorte B Bekker-Jensen,Melanie Blasius,Jesper V Olsen,Simon Bekker-Jensen

Frontiers in oncology 11:703501 PubMed34513683

2021

Integrated Bioinformatic Analysis of the Expression and Prognosis of Caveolae-Related Genes in Human Breast Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yao Tian,Xiaofeng Liu,Jing Hu,Huan Zhang,Baichuan Wang,Yingxi Li,Li Fu,Ran Su,Yue Yu
View all publications
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Product promise

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