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Rabbit Recombinant Monoclonal MURF1 antibody. Carrier free. Suitable for WB and reacts with Human, Mouse samples. Immunogen corresponding to Synthetic Peptide within Human TRIM63 conjugated to Keyhole Limpet Haemocyanin.

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Images

Western blot - Anti-MURF1 antibody [HL1450] - BSA and Azide free (AB313852), expandable thumbnail
  • Western blot - Anti-MURF1 antibody [HL1450] - BSA and Azide free (AB313852), expandable thumbnail

Key facts

Isotype

IgG

Host species

Rabbit

Storage buffer

pH: 7.4
Constituents: 100% PBS

Form

Liquid

Clonality

Monoclonal

Immunogen

  • Synthetic Peptide within Human TRIM63 conjugated to Keyhole Limpet Haemocyanin. Database link Q969Q1

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WB
Human
Tested
Mouse
Tested

Tested
Tested

Species

Human

Dilution info

1/500.00000 - 1/3000.00000

Notes

-

Species

Mouse

Dilution info

1/500.00000 - 1/3000.00000

Notes

-

Target data

Function

E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.

Targets

Trim63

Alternative names

Recommended products

Rabbit Recombinant Monoclonal MURF1 antibody. Carrier free. Suitable for WB and reacts with Human, Mouse samples. Immunogen corresponding to Synthetic Peptide within Human TRIM63 conjugated to Keyhole Limpet Haemocyanin.

Key facts

Isotype

IgG

Form

Liquid

Clonality

Monoclonal

Immunogen
  • Synthetic Peptide within Human TRIM63 conjugated to Keyhole Limpet Haemocyanin. Database link Q969Q1
Carrier free

Yes

Clone number

HL1450

Purification technique

Affinity purification Protein A

Concentration
Loading...

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

Aliquoting information

Upon delivery aliquot

Notes

This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. The carrier-free buffer and high concentration allow for increased conjugation efficiency.

This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

2 product images

  • Western blot - Anti-MURF1 antibody [HL1450] - BSA and Azide free (ab313852), expandable thumbnail

    Western blot - Anti-MURF1 antibody [HL1450] - BSA and Azide free (ab313852)

    All lanes: Western blot - Anti-MURF1 antibody [HL1450] - BSA and Azide free (ab313852) at 1/1000 dilution

    Lane 1: Mouse muscle tissue extract at 50 µg

    Lane 2: mouse liver tissue extract at 50 µg

    Secondary

    All lanes: HRP-conjugated anti-rabbit IgG antibody

    Predicted band size: 40 kDa

  • Western blot - Anti-MURF1 antibody [HL1450] - BSA and Azide free (ab313852), expandable thumbnail

    Western blot - Anti-MURF1 antibody [HL1450] - BSA and Azide free (ab313852)

    All lanes: Western blot - Anti-MURF1 antibody [HL1450] - BSA and Azide free (ab313852) at 1/1000 dilution

    All lanes: Human muscle tissue lysate at 10 µg

    Secondary

    All lanes: HRP-conjugated anti-rabbit IgG antibody

    Predicted band size: 40 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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