Rabbit Recombinant Monoclonal MURF1 antibody. Carrier free. Suitable for WB and reacts with Human, Mouse samples. Immunogen corresponding to Synthetic Peptide within Human TRIM63 conjugated to Keyhole Limpet Haemocyanin.
IgG
Rabbit
pH: 7.4
Constituents: 100% PBS
Liquid
Monoclonal
WB | |
---|---|
Human | Tested |
Mouse | Tested |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 1/500.00000 - 1/3000.00000 | Notes - |
Species Mouse | Dilution info 1/500.00000 - 1/3000.00000 | Notes - |
E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.
Trim63
IRF, MURF1, RNF28, SMRZ, TRIM63, E3 ubiquitin-protein ligase TRIM63, Iris RING finger protein, Muscle-specific RING finger protein 1, RING finger protein 28, RING-type E3 ubiquitin transferase TRIM63, Striated muscle RING zinc finger protein, Tripartite motif-containing protein 63, MuRF-1, MuRF1
Rabbit Recombinant Monoclonal MURF1 antibody. Carrier free. Suitable for WB and reacts with Human, Mouse samples. Immunogen corresponding to Synthetic Peptide within Human TRIM63 conjugated to Keyhole Limpet Haemocyanin.
IgG
Rabbit
pH: 7.4
Constituents: 100% PBS
Liquid
Monoclonal
Yes
HL1450
Affinity purification Protein A
Blue Ice
+4°C
+4°C
Upon delivery aliquot
This product is a recombinant monoclonal antibody, which offers several advantages including:
For more information, read more on recombinant antibodies.
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. The carrier-free buffer and high concentration allow for increased conjugation efficiency.
This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
All lanes: Western blot - Anti-MURF1 antibody [HL1450] - BSA and Azide free (ab313852) at 1/1000 dilution
Lane 1: Mouse muscle tissue extract at 50 µg
Lane 2: mouse liver tissue extract at 50 µg
All lanes: HRP-conjugated anti-rabbit IgG antibody
Predicted band size: 40 kDa
All lanes: Western blot - Anti-MURF1 antibody [HL1450] - BSA and Azide free (ab313852) at 1/1000 dilution
All lanes: Human muscle tissue lysate at 10 µg
All lanes: HRP-conjugated anti-rabbit IgG antibody
Predicted band size: 40 kDa
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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