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AB154515

Anti-MVK antibody

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(3 Publications)

Rabbit Polyclonal MVK antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human Mevalonate kinase aa 150 to C-terminus.

View Alternative Names

Mevalonate kinase, MK, MVK

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MVK antibody (AB154515)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MVK antibody (AB154515)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded A549 xenograft labeling MVK with ab154515 at 1/500.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human Mevalonate kinase aa 150 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q03426

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p>Alternatively Tris-EDTA buffer (pH8.0) may be used.</p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis (PubMed : 11278915, PubMed : 18302342, PubMed : 9325256, PubMed : 9392419).
See full target information Mevalonate kinase

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

PLoS pathogens 21:e1013164 PubMed40388397

2025

Hydrogen sulfide (H2S) coordinates redox balance, carbon metabolism, and mitochondrial bioenergetics to suppress SARS-CoV-2 infection.

Applications

Unspecified application

Species

Unspecified reactive species

Ragini Agrawal,Virender Kumar Pal,Suhas K S,Gopika Jayan Menon,Inder Raj Singh,Nitish Malhotra,Naren C S,Kailash Ganesh,Raju S Rajmani,Aswin Sai Narain Seshasayee,Nagasuma Chandra,Manjunath B Joshi,Amit Singh

Experimental and therapeutic medicine 28:361 PubMed39071912

2024

Sodium sulphate ameliorates hypercholesterolemia via the upregulation of in hepatocytes and alleviates hepatic insulin resistance via the downregulation of in mice with high cholesterol diets.

Applications

Unspecified application

Species

Unspecified reactive species

Yanhong Yang,Siping Yu,Hedong Rong,Zili Lei,Changyuan Yang,Huijuan Wu,Tianle Zhang,Fei Yang,Ya Nie,Lei Chen,Qing Hu,Qi Song,Jiao Guo

Frontiers in cell and developmental biology 10:927118 PubMed35912092

2022

Targeting of the Lipid Metabolism Impairs Resistance to BRAF Kinase Inhibitor in Melanoma.

Applications

Unspecified application

Species

Unspecified reactive species

Elisabetta Vergani,Giovanni L Beretta,Mariachiara Aloisi,Matteo Costantino,Cristina Corno,Simona Frigerio,Stella Tinelli,Matteo Dugo,Felice Maria Accattatis,Agnese Granata,Lorenzo Arnaboldi,Monica Rodolfo,Paola Perego,Laura Gatti
View all publications

Product promise

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