AB95926

Anti-MX1 antibody

Name: Anti-MX1 antibody (ab95926) | Abcam
Brand: Abcam Limited
SKU: AB95926
Rating: 5 (10 reviews)

(10 Reviews)

(55 Publications)

Anti-MX1 antibody (ab95926) is a rabbit polyclonal antibody detecting MX1 in Western Blot, IHC-P. Suitable for Human.

- Over 40 publications
- Trusted since 2010

View Alternative Names

Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA, Myxoma resistance protein 1, Myxovirus resistance protein 1, IFI-78K, MX1

3 Images

Supplier Data

Western blot - Anti-MX1 antibody (AB95926)

Lane 1:

Western blot - Anti-MX1 antibody (ab95926) at 1/1000 dilution

Lane 2:

Western blot - Anti-MX1 antibody (ab95926)

Lane 1:

293T whole cell lysate/extract at 30 µg

Lane 2:

Human MX-1 transfected 293T cells at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 76 kDa

false

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MX1 antibody (AB95926)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MX1 antibody (AB95926)

Immunohistochemical analysis of paraffin embedded MDA-MB-468 xenograft, using ab95926 at a 1/500 dilution.

Supplier Data

Western blot - Anti-MX1 antibody (AB95926)

All lanes:

Western blot - Anti-MX1 antibody (ab95926) at 1/5000 dilution

Lane 1:

H1299 cell lysate at 30 µg

Lane 2:

HeLa cell lysate at 30 µg

Lane 3:

Raji cell lysate at 30 µg

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human MX1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.

P20591

style

left-column

Alternative Products

Primary Antibodies

AB207414

Anti-MX1 antibody [EPR19967]

RabMAb|Recombinant

Immunoprecipitation - Anti-MX1 antibody [EPR19967] (AB207414)

Primary Antibodies

AB97921

Anti-MX1 antibody

Immunocytochemistry/ Immunofluorescence - Anti-MX1 antibody (AB97921)

Primary Antibodies

AB197205

Anti-MX1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MX1 antibody (AB197205)

Primary Antibodies

AB222856

Anti-MX1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MX1 antibody (AB222856)

Primary Antibodies

AB222492

Anti-MX1 antibody [EPR19967] - BSA and Azide free

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-MX1 antibody [EPR19967] - BSA and Azide free (AB222492)

Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

Primary Antibodies

AB224479

Anti-MX2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MX2 antibody (AB224479)

Primary Antibodies

AB9485

Anti-GAPDH antibody - Loading Control

BOND RX™ Validated|Lab Essentials

Primary Antibodies

AB76493

Anti-IRF3 (phospho S386) antibody [EPR2346]

20ul selling size|RabMAb|Recombinant

Western blot - Anti-IRF3 (phospho S386) antibody [EPR2346] (AB76493)

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }

style

left-column

Product details

What is this antibody validated in?
Anti-MX1 antibody (ab95926) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human samples.

What is the molecular weight of MX1?
Anti-MX1 (ab95926) specifically detects a band for MX1 (UniProt: P20591) at a molecular weight of 76kDa.

Trusted by the scientific community
Anti-MX1 (ab95926) was first used in a scientific publication in 2010 and has been cited over 40 times in peer-reviewed journals.

Reviewed by scientists
Anti-MX1 (ab95926) has over 10 independent reviews from customers.

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

Purified by antigen affinity chromatography.

Storage buffer

pH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

See full target information MX1

style

left-column

Publications (55)

Recent publications for all applications. Explore the full list and refine your search

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 133:e70034 PubMed40518873

2025

Immunohistochemical Profiling of Interferon-Stimulated Genes in Histopathological Specimens: A Potential Screening Approach for Viral Infections.

Applications

Unspecified application

Species

Unspecified reactive species

Christian Thomsen,Svend Birkelund,Rasmus Røge

Arthritis research & therapy 27:110 PubMed40389992

2025

Clinicopathological profile of eosinophilic fasciitis: a retrospective cohort study from a neuromuscular disorder center in China.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoyuan Wang,Lining Zhang,Ying Hou,Tingjun Dai,Xiaotian Ma,Kai Shao,Chuanzhu Yan,Bing Zhao

Arthritis research & therapy 26:215 PubMed39695751

2024

Development of differential diagnostic models for distinguishing between limb-girdle muscular dystrophy and idiopathic inflammatory myopathy.

Applications

Unspecified application

Species

Unspecified reactive species

Guangyu Wang,Lijun Fu,Lining Zhang,Kai Shao,Ying Hou,Tingjun Dai,Pengfei Lin,Chuanzhu Yan,Bing Zhao

Frontiers in immunology 15:1458967 PubMed39351233

2024

Varicella-zoster virus recapitulates its immune evasive behaviour in matured hiPSC-derived neurospheroids.

Applications

Unspecified application

Species

Unspecified reactive species

Jonas Govaerts,Elise Van Breedam,Sarah De Beuckeleer,Charlotte Goethals,Claudio Peter D'Incal,Julia Di Stefano,Siebe Van Calster,Tamariche Buyle-Huybrecht,Marlies Boeren,Hans De Reu,Søren R Paludan,Marc Thiry,Marielle Lebrun,Catherine Sadzot-Delvaux,Helena Motaln,Boris Rogelj,Johan Van Weyenbergh,Winnok H De Vos,Wim Vanden Berghe,Benson Ogunjimi,Peter Delputte,Peter Ponsaerts

iScience 27:110525 PubMed39156641

2024

Pandemic-associated pernio harbors footprints of an abortive SARS-CoV-2 infection.

Applications

Unspecified application

Species

Unspecified reactive species

Lisa M Arkin,Ana C Costa-da-Silva,Justin Frere,Ashley Ng,Rubina Sharma,John J Moon,Hailey E Bussan,Clara H Kim,Ayesha Javaid,Olivia R Steidl,Ahmad Yatim,Fanny Saidoune,Michel Gilliet,Joe T Nguyen,Aman Nihal,George Luong,Meaghan Kenfield,Lucia Carrau,Jennifer M Tran,Molly A Hinshaw,Erin G Brooks,Jose M Ayuso,David H O'Connor,Jean-Laurent Casanova,Edward W Cowen,Beth A Drolet,Anne Marie Singh,Benjamin tenOever,Jacqueline W Mays

CNS neuroscience & therapeutics 30:e14882 PubMed39097917

2024

Clinico-sero-pathological profiles and risk prediction model of idiopathic inflammatory myopathy (IIM) patients with different perifascicular changes.

Applications

Unspecified application

Species

Unspecified reactive species

Lining Zhang,Lijun Fu,Guoyong Zhang,Ying Hou,Xiaotian Ma,Dandan Zhao,Wei Li,Tingjun Dai,Qiang Shu,Chuanzhu Yan,Bing Zhao

Arthritis & rheumatology (Hoboken, N.J.) 76:78-91 PubMed37488975

2023

Endothelial Response to Type I Interferon Contributes to Vasculopathy and Fibrosis and Predicts Disease Progression of Systemic Sclerosis.

Applications

Unspecified application

Species

Unspecified reactive species

Hanlin Yin,Oliver Distler,Lichong Shen,Xiaojiang Xu,Ye Yuan,Rui Li,Bei Liu,Qianqian Li,Qianru Huang,Feng Xie,Zhiliang Zhang,Rui Liang,Xueyu Dai,Xiaoxiang Chen,Bin Li,Qingran Yan,Liangjing Lu

mBio 14:e0100723 PubMed37345956

2023

SARS-CoV-2 hijacks p38β/MAPK11 to promote virus replication.

Applications

Unspecified application

Species

Unspecified reactive species

Christina A Higgins,Benjamin E Nilsson-Payant,Boris Bonaventure,Andrew P Kurland,Chengjin Ye,Tomer M Yaron,Jared L Johnson,Prithy Adhikary,Ilona Golynker,Maryline Panis,Oded Danziger,Brad R Rosenberg,Lewis C Cantley,Luis Martínez-Sobrido,Benjamin tenOever,Jeffrey R Johnson

Journal of clinical immunology 43:808-818 PubMed36753016

2023

Type I Interferonopathy due to a Homozygous Loss-of-Inhibitory Function Mutation in STAT2.

Applications

Unspecified application

Species

Unspecified reactive species

Gaofeng Zhu,Mihaly Badonyi,Lina Franklin,Luis Seabra,Gillian I Rice, Anne-Boland-Auge,Jean-François Deleuze,Salima El-Chehadeh,Mathieu Anheim,Anne de Saint-Martin,Sandra Pellegrini,Joseph A Marsh,Yanick J Crow,Marie-Therese El-Daher

iScience 26:106019 PubMed36866043

2023

Single-cell RNA-seq analysis reveals dual sensing of HIV-1 in blood Axl dendritic cells.

Applications

Unspecified application

Species

Unspecified reactive species

Flavien Brouiller,Francesca Nadalin,Pierre-Emmanuel Bonté,Ouardia Ait-Mohamed,Constance Delaugerre,Jean-Daniel Lelièvre,Florent Ginhoux,Nicolas Ruffin,Philippe Benaroch

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com