Anti-MX1 antibody (ab95926) is a rabbit polyclonal antibody detecting MX1 in Western Blot, IHC-P. Suitable for Human.
- Over 40 publications
- Trusted since 2010
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- Journal of clinical immunology 43:808-8182023Type I Interferonopathy due to a Homozygous Loss-of-Inhibitory Function Mutation in STAT2.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGaofeng Zhu,Mihaly Badonyi,Lina Franklin,Luis Seabra,Gillian I Rice, Anne-Boland-Auge,Jean-François Deleuze,Salima El-Chehadeh,Mathieu Anheim,Anne de Saint-Martin,Sandra Pellegrini,Joseph A Marsh,Yanick J Crow,Marie-Therese El-DaherPubMed 36753016
- iScience 26:1060192023Single-cell RNA-seq analysis reveals dual sensing of HIV-1 in blood Axl dendritic cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesFlavien Brouiller,Francesca Nadalin,Pierre-Emmanuel Bonté,Ouardia Ait-Mohamed,Constance Delaugerre,Jean-Daniel Lelièvre,Florent Ginhoux,Nicolas Ruffin,Philippe BenarochPubMed 36866043
- Immunity 55:2074-2084.e52022Excessive negative regulation of type I interferon disrupts viral control in individuals with Down syndrome.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLouise Malle,Marta Martin-Fernandez,Sofija Buta,Ashley Richardson,Douglas Bush,Dusan BogunovicPubMed 36243008
- Veterinary medicine and science 8:2444-24502022Investigation of the anti-pseudorabies virus activity of interferon lambda 3 in cultured porcine kidney epithelial cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHuidan Deng,Zhijie Jian,Ling Zhu,Fengqin Li,Jun Zhao,Junliang Deng,Xiangang Sun,Zhiwen XuPubMed 36122903
- Journal of clinical laboratory analysis 36:e246312022Activation of cGAS-STING pathway - A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMeichen Zhou,Xiaoxiao Cheng,Wenhua Zhu,Jianhua Jiang,Sijia Zhu,Xuan Wu,Meirong Liu,Qi FangPubMed 36030554
- Nature cancer 3:961-9752022Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYun Wei,Qian Qin,Chuan Yan,Madeline N Hayes,Sara P Garcia,Haibin Xi,Daniel Do,Alexander H Jin,Tiffany C Eng,Karin M McCarthy,Abhinav Adhikari,Maristela L Onozato,Dimitrios Spentzos,Gunnlaugur P Neilsen,A John Iafrate,Leonard H Wexler,April D Pyle,Mario L Suvà,Filemon Dela Cruz,Luca Pinello,David M LangenauPubMed 35982179
- PLoS pathogens 18:e10106322022Comparison of tissue tropism and host response to enteric and respiratory enteroviruses.Applications:Unspecified applicationReactive species:Unspecified reactive speciesInes Cordeiro Filipe,Han Kang Tee,Julien Prados,Isabelle Piuz,Samuel Constant,Song Huang,Caroline TapparelPubMed 35789345
- PLoS pathogens 18:e10104052022ISG15 deficiency restricts HIV-1 infection.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDenise Jurczyszak,Lara Manganaro,Sofija Buta,Conor Gruber,Marta Martin-Fernandez,Justin Taft,Roosheel S Patel,Melissa Cipolla,Hala Alshammary,Lubbertus C F Mulder,Ravi Sachidanandam,Dusan Bogunovic,Viviana SimonPubMed 35333911
- Cancer research 82:1283-12972022Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJaione Auzmendi-Iriarte,Maddalen Otaegi-Ugartemendia,Estefania Carrasco-Garcia,Mikel Azkargorta,Antonio Diaz,Ander Saenz-Antoñanzas,Joaquin Andrés Andermatten,Mikel Garcia-Puga,Idoia Garcia,Alejandro Elua-Pinin,Irune Ruiz,Nicolas Sampron,Felix Elortza,Ana Maria Cuervo,Ander MatheuPubMed 35131870
- The Journal of general virology 102:2021Multiple RNA virus matrix proteins interact with SLD5 to manipulate host cell cycle.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLi Zhu,Xinyu Li,Henan Xu,Lifeng Fu,George Fu Gao,Wenjun Liu,Linqing Zhao,Xiaojun Wang,Wei Jiang,Min FangPubMed 34882534
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 20% Glycerol (glycerin, glycerine), 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human MX1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information. Database link P20591
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Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500 - 1/3000 | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
Associated Products
Select an associated product type
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Target data
Function
Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.
Alternative names
Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA, Myxoma resistance protein 1, Myxovirus resistance protein 1, IFI-78K, MX1
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Anti-MX1 antibody (ab95926) is a rabbit polyclonal antibody detecting MX1 in Western Blot, IHC-P. Suitable for Human.
- Over 40 publications
- Trusted since 2010
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 20% Glycerol (glycerin, glycerine), 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human MX1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information. Database link P20591
- Purification technique
- Affinity purification Immunogen
- Concentration
- Purification notes
Purified by antigen affinity chromatography.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Anti-MX1 antibody (ab95926) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human samples.
What is the molecular weight of MX1?
Anti-MX1 (ab95926) specifically detects a band for MX1 (UniProt: P20591) at a molecular weight of 76kDa.
Trusted by the scientific community
Anti-MX1 (ab95926) was first used in a scientific publication in 2010 and has been cited over 40 times in peer-reviewed journals.
Reviewed by scientists
Anti-MX1 (ab95926) has over 10 independent reviews from customers.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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3 product images
Western blot - Anti-MX1 antibody (ab95926)
Lane 1: Western blot - Anti-MX1 antibody (ab95926) at 1/1000 dilution
Lane 2: Western blot - Anti-MX1 antibody (ab95926)
Lane 1: 293T whole cell lysate/extract at 30 µg
Lane 2: Human MX-1 transfected 293T cells at 30 µg
SecondaryAll lanes: HRP-conjugated anti-rabbit IgG antibody
Predicted band size: 76 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MX1 antibody (ab95926)
Immunohistochemical analysis of paraffin embedded MDA-MB-468 xenograft, using ab95926 at a 1/500 dilution.
Western blot - Anti-MX1 antibody (ab95926)
All lanes: Western blot - Anti-MX1 antibody (ab95926) at 1/5000 dilution
Lane 1: H1299 cell lysate at 30 µg
Lane 2: HeLa cell lysate at 30 µg
Lane 3: Raji cell lysate at 30 µg
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