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AB108522

Anti-MYBPC3 antibody [EPR3008(2)]

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(2 Publications)

Rabbit Recombinant Monoclonal MYBPC3 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications.

View Alternative Names

Cardiac MyBP-C, MYBPC3

2 Images
Western blot - Anti-MYBPC3 antibody [EPR3008(2)] (AB108522)
  • WB

Unknown

Western blot - Anti-MYBPC3 antibody [EPR3008(2)] (AB108522)

All lanes:

Western blot - Anti-MYBPC3 antibody [EPR3008(2)] (ab108522) at 1/1000 dilution

All lanes:

Human heart tissue lysate at 10 µg

Predicted band size: 141 kDa

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Western blot - Anti-MYBPC3 antibody [EPR3008(2)] (AB108522)
  • WB

Lab

Western blot - Anti-MYBPC3 antibody [EPR3008(2)] (AB108522)

Blocking and dilution buffer : 5% NFDM /TBST.

All lanes:

Western blot - Anti-MYBPC3 antibody [EPR3008(2)] (ab108522) at 1/5000 dilution

All lanes:

Human heart tissue lysate at 10 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Predicted band size: 141 kDa

Observed band size: 141 kDa

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  • Carrier free

    Anti-MYBPC3 antibody [EPR3008(2)] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR3008(2)

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
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Product details

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Stable for 12 months at -20°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
See full target information MYBPC3
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Cell reports. Medicine 5:101520 PubMed38642550

2024

Myosin inhibitor reverses hypertrophic cardiomyopathy in genotypically diverse pediatric iPSC-cardiomyocytes to mirror variant correction.

Applications

Unspecified application

Species

Unspecified reactive species

Caroline Kinnear,Abdelrahman Said,Guoliang Meng,Yimu Zhao,Erika Y Wang,Naimeh Rafatian,Neha Parmar,Wei Wei,Filio Billia,Craig A Simmons,Milica Radisic,James Ellis,Seema Mital

Cancer drug resistance (Alhambra, Calif.) 2:335-350 PubMed35582720

2019

Daunorubicin can eliminate iPS-derived cancer stem cells via ICAD/CAD-independent DNA fragmentation.

Applications

Unspecified application

Species

Unspecified reactive species

Akimasa Seno,Akifumi Mizutani,Kazuki Aizawa,Ryoma Onoue,Junko Masuda,Naotaka Ochi,Saki Taniguchi,Tatsuyuki Sota,Yuki Hiramoto,Taisuke Michiue,Neha Nair,Masaharu Seno
View all publications
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Complementary Products

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com