AB10910

Anti-Myc tag antibody [JAC6]

Lab Essentials
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(12 Publications)

Rat Monoclonal C-Myc/MYC antibody. Suitable for IP, WB, IHC-Fr and reacts with Human samples. Cited in 12 publications. Immunogen corresponding to Synthetic Peptide within Human MYC aa 400 to C-terminus.

View Alternative Names

BHLHE39, MYC, Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, Proto-oncogene c-Myc, Transcription factor p64, bHLHe39

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

JAC6

Isotype

IgG1

Carrier free

Reacts with

Human

Applications

IHC-Fr, WB, IP

applications

Immunogen

Synthetic Peptide within Human MYC aa 400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P01106

Specificity

This antibody recognises the myc epitope which is frequently used to tag proteins, and is the same epitope recognised by clone 9E10.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" } } }

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Product details

This product should be stored undiluted. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Purification notes

Purified from tissue culture supernatent.

Storage buffer

Preservative: 0.09% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed : 24940000, PubMed : 25956029). Activates the transcription of growth-related genes (PubMed : 24940000, PubMed : 25956029). Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed : 24940000, PubMed : 25956029). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity). Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (PubMed : 20010808).

See full target information MYC

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Publications (12)

Recent publications for all applications. Explore the full list and refine your search

Science advances 8:eabg3203 PubMed36070378

2022

A neurogenetic mechanism of experience-dependent suppression of aggression.

Applications

Unspecified application

Species

Unspecified reactive species

Kenichi Ishii,Matteo Cortese,Xubo Leng,Maxim N Shokhirev,Kenta Asahina

Pharmaceutical biology 60:417-426 PubMed35175172

2022

Osthole exhibits an antitumor effect in retinoblastoma through inhibiting the PI3K/AKT/mTOR pathway via regulating the hsa_circ_0007534/miR-214-3p axis.

Applications

Unspecified application

Species

Unspecified reactive species

Xiufang Lv,Haojiang Yang,Hui Zhong,Li He,Li Wang

Molecular cell 69:744-756.e6 PubMed29456190

2018

PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions.

Applications

Unspecified application

Species

Unspecified reactive species

Pei-I Tsai,Chin-Hsien Lin,Chung-Han Hsieh,Amanda M Papakyrikos,Min Joo Kim,Valerio Napolioni,Carmen Schoor,Julien Couthouis,Ruey-Meei Wu,Zbigniew K Wszolek,Dominic Winter,Michael D Greicius,Owen A Ross,Xinnan Wang

Development (Cambridge, England) 145: PubMed29229771

2018

female-specific Ilp7 motoneurons are generated by Fruitless-dependent cell death in males and by a double-assurance survival role for Transformer in females.

Applications

Unspecified application

Species

Unspecified reactive species

Sarah Rose C Garner,Monica C Castellanos,Katherine E Baillie,Tianshun Lian,Douglas W Allan

The Journal of biological chemistry 292:19290-19303 PubMed28978649

2017

Reconstitution of the core of the malaria parasite glideosome with recombinant class XIV myosin A and actin.

Applications

Species

Unspecified reactive species

Carol S Bookwalter,Chwen L Tay,Rama McCrorie,Michael J Previs,Hailong Lu,Elena B Krementsova,Patricia M Fagnant,Jake Baum,Kathleen M Trybus

Journal of cell science 128:4063-73 PubMed26430213

2015

Regulation of polycystin-1 ciliary trafficking by motifs at its C-terminus and polycystin-2 but not by cleavage at the GPS site.

Applications

Species

Mouse

Xuefeng Su,Maoqing Wu,Gang Yao,Wassim El-Jouni,Chong Luo,Azadeh Tabari,Jing Zhou

Current biology : CB 24:242-51 PubMed24440391

2014

Cellular and behavioral functions of fruitless isoforms in Drosophila courtship.

Applications

IHC

Species

Unspecified reactive species

Anne C von Philipsborn,Sabrina Jörchel,Laszlo Tirian,Ebru Demir,Tomoko Morita,David L Stern,Barry J Dickson

The Journal of biological chemistry 286:17205-16 PubMed21454556

2011

Critical role of the beta-subunit CDC50A in the stable expression, assembly, subcellular localization, and lipid transport activity of the P4-ATPase ATP8A2.

Applications

IHC-Fr

Species

Unspecified reactive species

Jonathan A Coleman,Robert S Molday

The Plant journal : for cell and molecular biology 63:662-9 PubMed20545889

2010

The hydroxyproline-rich glycoprotein domain of the Arabidopsis LRX1 requires Tyr for function but not for insolubilization in the cell wall.

Applications

Species

Unspecified reactive species

Christoph Ringli

PLoS pathogens 5:e1000539 PubMed19662167

2009

Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector.

Applications

Species

Unspecified reactive species

Ellen S C Bushell,Andrea Ecker,Timm Schlegelmilch,David Goulding,Gordon Dougan,Robert E Sinden,George K Christophides,Fotis C Kafatos,Dina Vlachou

View all publications

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