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AB53600

Anti-Mycoplasma pneumoniae antibody

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(3 Publications)

Rabbit Polyclonal Mycoplasma pneumoniae antibody. Suitable for ELISA, WB and reacts with Mycoplasma pneumoniae samples. Cited in 3 publications.

View Alternative Names

M. pneumoniae, bacterial pneumonia

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mycoplasma pneumoniae

Applications

WB, ELISA

applications

Specificity

ab53600 is specific for all antigens of Mycoplasma pneumoniae.

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Reactivity data

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Properties and storage information

Form
Liquid
Purification notes
ab53600 is purified (>95%)
Storage buffer
pH: 7.2 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Stable for 12 months at -20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Mycoplasma pneumoniae an atypical bacterium lacking a cell wall measures around 0.2 to 0.3 micrometers in size. It is commonly referred to as an "antibiotic-resistant pathogen." Mycoplasma pneumoniae localizes to the respiratory tract where it attaches to epithelial cells using specialized adhesion proteins. It interacts directly with the host cells impairing ciliary function and contributing to respiratory system inflammation. This bacterium has adapted to evade immune responses presenting challenges in treatment due to its resistance to cell wall-targeting antibiotics such as beta-lactams.
Biological function summary

Mycoplasma pneumoniae engages in several cellular processes that contribute to its pathogenesis. It does not appear to be part of a larger protein complex but utilizes a unique set of proteins for adherence and evasion of the immune response. This organism generates reactive oxygen species as byproducts which lead to tissue damage and dysfunction within host tissues. It has evolved mechanisms to modulate host immune reactions allowing it to persist and maintain infections over extended periods.

Pathways

Several associated with Mycoplasma pneumoniae are involved in immune modulation and inflammation. For instance it involves pathways related to cytokine production and epithelial cell signaling. These pathways interact with host proteins such as toll-like receptors augmenting the inflammatory response. Mycoplasma pneumoniae affects these signaling pathways influencing not only the localized respiratory tract environment but potentially broader systemic responses in the host.

Mycoplasma pneumoniae is notably associated with respiratory infections such as atypical pneumonia and it may contribute to the exacerbation of asthma symptoms. During infection it can interact with proteins like interleukin-6 in the inflammatory cascade potentially leading to heightened inflammatory responses. These interactions complicate underlying respiratory conditions making infections more severe and prolonged. Understanding these relationships highlights the need for developing specific anti-Mycoplasma pneumoniae antibodies and diagnostic tools to manage and treat infections effectively.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Mycoplasma pneumoniae
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 26: PubMed40650312

2025

An mRNA Vaccine Targeting the C-Terminal Region of P1 Protein Induces an Immune Response and Protects Against .

Applications

Unspecified application

Species

Unspecified reactive species

Fenglian Zhang,Chengwei Li,Yanan Wu,Hongyun Chuan,Shaohui Song,Yun Xie,Qi Zhu,Qianqian Chen,Fei Tong,Runfang Zhang,Guangbo Yuan,Xiaoyan Wu,Jian Zhou,Guoyang Liao

International journal of molecular sciences 24: PubMed37239946

2023

Extracellular Vesicles Released from Macrophages Infected with Stimulate Proinflammatory Response via the TLR2-NF-κB/JNK Signaling Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Chunji Ma,Xiujing Hao,Liyang Gao,Yongyu Wang,Juan Shi,Haixia Luo,Min Li

PloS one 7:e34080 PubMed22479529

2012

Silencing of renal DNaseI in murine lupus nephritis imposes exposure of large chromatin fragments and activation of Toll like receptors and the Clec4e.

Applications

Unspecified application

Species

Unspecified reactive species

Dhivya Thiyagarajan,Silje Fismen,Natalya Seredkina,Søren Jacobsen,Thomas Elung-Jensen,Anne-Lise Kamper,Christopher Graham Fenton,Ole Petter Rekvig,Elin Synnøve Mortensen
View all publications
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Product promise

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