Rabbit Polyclonal Myoneurin antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MYNN aa 50-350.
View Alternative Names
OSZF, ZBTB31, SBBIZ1, MYNN, Myoneurin, Zinc finger and BTB domain-containing protein 31
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myoneurin antibody (AB238912)
Paraffin-embedded human placenta tissue stained for Myoneurin using ab238912 at 1/100 dilution in immunohistochemical analysis.
Reactivity data
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Supplementary information
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Biological function summary
Myoneurin contributes to regulating gene expression. It acts as a part of multi-protein complexes required in nucleosome remodeling and transcription activation. Through these complexes Myoneurin alters chromatin structure facilitating the accessibility of transcription factors to DNA. This function is important for the fine-tuning of gene expression that affects cell cycle progression and differentiation especially within muscular and neural contexts.
Pathways
Several processes partly depend on Myoneurin. Notably it involves the muscle cell differentiation pathway and neural development. It interacts with proteins such as MEF2 a transcription factor that modulates gene expression in muscle cells and CREB implicated in long-term memory formation both participating in gene regulatory networks coordinated by Myoneurin. These interactions suggest its role in gene pathways that govern tissue-specific functional outcomes.
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Target data
Publications (1)
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International journal of biological sciences 20:1045-1063 PubMed38322121
2024
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