Anti-N6-methyladenosine (m6A) antibody [17-3-4-1]
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(174 Publications)
Anti-N6-methyladenosine (m6A) antibody [17-3-4-1] (ab208577) is a mouse monoclonal antibody detecting N6-methyladenosine (m6A) in IP.
- Over 60 publications
View Alternative Names
N6-methyladenosine, m6A
- IP
Supplier Data
Immunoprecipitation - Anti-N6-methyladenosine (m6A) antibody [17-3-4-1] (AB208577)
N6-methyladenosine (m6A) was immunoprecipitated using ab208577 from radiolabeled synthetic methylated transcript (Bound); radiolabeled Non methylated control (Non bound) and radiolabeled Input RNA control.
All lanes:
Immunoprecipitation - Anti-N6-methyladenosine (m6A) antibody [17-3-4-1] (ab208577)
false
- SB
Supplier Data
Southern Blot - Anti-N6-methyladenosine (m6A) antibody [17-3-4-1] (AB208577)
Lane 1 Single stranded DNA
Lane 2 Double stranded DNA
Labelled with ab208577. Arrow shows m6A containing fragment.
- Northwestern
Supplier Data
Northwestern blot - Anti-N6-methyladenosine (m6A) antibody [17-3-4-1] (AB208577)
Use of ab208577 for northwestern blot using synthetic methlyated and non methlyated RNA.
Reactivity data
Product details
Anti-N6-methyladenosine (m6A) antibody [17-3-4-1] (ab208577) is a mouse monoclonal antibody and is validated for use in Immunoprecipitation (IP). Trusted by the scientific community
Anti-N6-methyladenosine (m6A) [17-3-4-1] (ab208577) was first used in a scientific publication in 2015 and has been cited over 60 times in peer-reviewed journals.
Properties and storage information
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Appropriate long-term storage conditions
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Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
M6A methylation affects mRNA processing stability translation and decay. It integrates into large multi-protein complexes where it influences gene expression outcomes by affecting the RNA's interaction with the cellular machinery. This methylation modification acts as a regulatory signal that influences essential processes such as cell differentiation and circadian rhythms. Elucidating the biological functions of m6A involves studying how it affects RNA fate and its downstream gene regulatory networks.
Pathways
M6A modification is central to the mRNA metabolic pathway and the PI3K-Akt signaling pathway. It interacts with various proteins such as METTL3 an m6A methyltransferase which is vital for mediating m6A modification. It also interacts with YTH domain-containing proteins that recognize m6A marks influencing transcript dynamics and gene expression. The interplay of m6A with proteins in these pathways underlines its role in fine-tuning cellular processes and responses.
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Publications (174)
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Kidney diseases (Basel, Switzerland) 11:543-559 PubMed41064102
2025
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Journal of cellular and molecular medicine 29:e70829 PubMed40913254
2025
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Cell death discovery 11:417 PubMed40883266
2025
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Cell & bioscience 15:124 PubMed40877964
2025
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BMC biology 23:257 PubMed40817234
2025
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The world journal of men's health : PubMed40676888
2025
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Hereditas 162:123 PubMed40640957
2025
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Scientific reports 15:24858 PubMed40640307
2025
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Cell biology international 49:1290-1300 PubMed40600388
2025
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Molecular biomedicine 6:44 PubMed40555877
2025
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Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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