Anti-Nance-Horan Syndrome Protein antibody
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(1 Publication)
Rabbit Polyclonal Nance-Horan Syndrome Protein antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human NHS aa 1100 to C-terminus.
View Alternative Names
Actin remodeling regulator NHS, Congenital cataracts and dental anomalies protein, Nance-Horan syndrome protein, NHS
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Nance-Horan Syndrome Protein antibody (AB122177)
ab122177 at 1/35 dilution staining Nance-Horan Syndrome Protein in Paraffin-embedded Human Liver tissue by Immunohistochemistry.
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-Nance-Horan Syndrome Protein antibody (AB122177)
Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus but not nucleoli. Recommended concentration of ab122177 1-4 µg/ml. Cells treated with PFA/Triton X-100.
Reactivity data
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Supplementary information
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Biological function summary
The Nance-Horan Syndrome Protein is involved in cell differentiation and development. It acts as part of a larger protein complex that regulates cellular stability and morphology. This involvement is essential in maintaining the integrity of tissues particularly in areas like the eye lens and dental structures where precise cell architecture is significant for function. The protein's specific interactions in these biological processes highlight its importance within dynamic cellular environments.
Pathways
The Nance-Horan Syndrome Protein intersects with developmental signaling pathways. It particularly associates with the Wnt signaling pathway which is critical for tissue morphogenesis and cell fate determination. In this pathway NHS interacts with proteins such as β-catenin helping regulate gene expression and maintaining tissue-specific functions. The NHS protein's activity within this pathway supports the development of anatomical structures necessitating precise cellular communication.
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Target data
Publications (1)
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International journal of oncology 64: PubMed38426627
2024
Applications
Unspecified application
Species
Unspecified reactive species
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