Anti-Nanog antibody
4
(18 Reviews)
|
(426 Publications)
Anti-Nanog antibody (ab80892) is a rabbit polyclonal antibody detecting Nanog in Western Blot, Flow Cytometry, IHC-P, IHC- Wmt, ICC/IF. Suitable for Mouse.
- Over 360 publications
- Trusted since 2009
View Alternative Names
Ecat4, Enk, Nanog, Homeobox protein NANOG, ES cell-associated protein 4, Early embryo specific expression NK-type homeobox protein, Homeobox transcription factor Nanog
Reactivity data
Product details
Anti-Nanog antibody (ab80892) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC - Wmt), Immunocytochemistry/immunofluorescence (ICC/IF) in Mouse samples.
Trusted by the scientific community
Anti-Nanog (ab80892) was first used in a scientific publication in 2009 and has been cited over 360 times in peer-reviewed journals.
Reviewed by scientists
Anti-Nanog (ab80892) has over 15 independent reviews from customers.
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Nanog plays a central role in stem cell biology operating as part of a complex regulatory network. Nanog interacts with other important transcription factors like Oct4 and Sox2 forming a core pluripotency network. This network suppresses the differentiation of stem cells by regulating the expression of genes involved in cell fate decisions. By modulating the expression of different pathways Nanog ensures the maintenance of an undifferentiated state in stem cells.
Pathways
Nanog is deeply embedded in the Wnt/Β-Catenin and TGF-Β signaling pathways important for stem cell maintenance and differentiation. In the Wnt/Β-Catenin pathway Nanog works alongside proteins like Β-catenin to drive the expression of genes that promote self-renewal. Meanwhile in the TGF-Β pathway Nanog acts with proteins such as Smad2/3 to balance pluripotency and differentiation signals. These pathways critically support the complex network that sustains stem cell identity and function.
Product protocols
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Target data
Publications (426)
Recent publications for all applications. Explore the full list and refine your search
Frontiers in cell and developmental biology 13:1640986 PubMed40874021
2025
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Nature communications 16:7071 PubMed40750602
2025
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Scientific reports 15:26163 PubMed40681589
2025
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Nucleic acids research 53: PubMed40521666
2025
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology 39:e70723 PubMed40497397
2025
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World journal of clinical pediatrics 14:101080 PubMed40491730
2025
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Scientific reports 15:14675 PubMed40287470
2025
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iScience 28:111671 PubMed39868030
2025
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Veterinary sciences 12: PubMed39852882
2025
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Molecular therapy : the journal of the American Society of Gene Therapy 33:1213-1225 PubMed39797398
2025
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Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com