Chicken Polyclonal NeuN antibody. Neuron marker. Suitable for IHC-P, WB and reacts with Human, Mouse, Rat samples. Cited in 34 publications. Immunogen corresponding to Synthetic Peptide within Mouse Rbfox3 conjugated to Keyhole Limpet Haemocyanin.
View Alternative Names
RNA binding protein fox-1 homolog 3, Fox-1 homolog C, Neuronal nuclei antigen, NeuN antigen, RBFOX3
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NeuN antibody - Neuronal Marker (AB134014)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of adult mouse CA1 hippocampus tissue labelling NeuN (red) with ab134014. Tissue was fixed with 4% paraformaldehyde. Green - rabbit anti-Beta-Tubulin 3.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NeuN antibody - Neuronal Marker (AB134014)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of adult mouse cerebral cortex tissue labelling NeuN (red) with ab134014. Tissue was fixed with 4% paraformaldehyde. Green - rabbit anti-Beta-Tubulin 3.
- WB
Ap
Western blot - Anti-NeuN antibody - Neuronal Marker (AB134014)
All lanes:
Western blot - Anti-NeuN antibody - Neuronal Marker (ab134014) at 1/1000 dilution
Lane 1:
Mouse Brain at 20 µg
Lane 2:
Rat Brain at 20 µg
Predicted band size: 34 kDa
Observed band size: 42 kDa
false
Reactivity data
Properties and storage information
Form
Purification technique
Purification notes
Storage buffer
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
NeuN plays an essential role in the regulation of RNA-binding influencing the splicing and stability of transcripts. It forms part of the complex network responsible for managing neuron-specific gene expression. By interacting with other RNA-binding proteins NeuN contributes to the fine-tuning needed for proper neuronal development and function. As a result NeuN helps maintain the health and activity of nerve cells allowing them to perform complex neurological tasks.
Pathways
NeuN has a significant role in neuronal differentiation and plasticity pathways. NeuN coordinates with elements of the Notch signaling pathway which is important for guiding cell fate decisions in the nervous system. It also interacts with related proteins like Fox proteins involved in splicing regulation. These pathways ensure neurons develop differentiate and function correctly within the nervous system's precise architecture.
Product protocols
- Visit the General protocols
- Visit the Troubleshooting
Target data
Publications (34)
Recent publications for all applications. Explore the full list and refine your search
Journal of neuroinflammation 22:170 PubMed40581646
2025
Applications
Unspecified application
Species
Unspecified reactive species
Scientific reports 14:25305 PubMed39455718
2024
Applications
Unspecified application
Species
Unspecified reactive species
Journal of extracellular vesicles 13:e12439 PubMed38647111
2024
Applications
Unspecified application
Species
Unspecified reactive species
International journal of nanomedicine 19:2265-2284 PubMed38476273
2024
Applications
Unspecified application
Species
Unspecified reactive species
Molecular brain 17:5 PubMed38317261
2024
Applications
Unspecified application
Species
Unspecified reactive species
GeroScience 46:2503-2519 PubMed37989825
2023
Applications
Unspecified application
Species
Unspecified reactive species
Science immunology 8:eadg2979 PubMed37862432
2023
Applications
Unspecified application
Species
Unspecified reactive species
The Journal of clinical investigation 133: PubMed36719741
2023
Applications
Unspecified application
Species
Unspecified reactive species
iScience 26:106152 PubMed36879821
2023
Applications
Unspecified application
Species
Unspecified reactive species
Neurotoxicology 94:98-107 PubMed36402194
2022
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com