Anti-Neuropeptide S antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Neuropeptide S impacts the brain's response to stress and emotion regulation. It does not form part of a complex rather it binds directly with its receptor to initiate signaling cascades. NPS can enhance arousal and promote wakefulness which affects the sleep-wake cycle and stress response. The activation of NPSR1 by Neuropeptide S also plays a role in reducing anxiety-like behaviors. Through these functions Neuropeptide S influences various behavioral and physiological processes.

Pathways

Neuropeptide S notably contributes to the stress response pathway and the modulation of anxiety. It interacts mainly through the cyclic AMP-protein kinase A (cAMP-PKA) pathway. Neuropeptide S modulates the release of neurotransmitters serotonin and noradrenaline through these signaling processes thereby affecting mood and alertness. These pathways interconnect with those of other neurotransmitters facilitating complex brain functions and responses.