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AB219600

Anti-NK-1R antibody - Extracellular domain

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(4 Publications)

Rabbit Polyclonal NK-1R antibody. Extracellular domain. Suitable for IHC-P and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human TACR1.

View Alternative Names

NK1R, TAC1R, TACR1, Substance-P receptor, SPR, NK-1 receptor, Tachykinin receptor 1, NK-1R

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NK-1R antibody - Extracellular domain (AB219600)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NK-1R antibody - Extracellular domain (AB219600)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain glioblastoma tissue labeling NK-1R with ab219600 at 4 μg/mL.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NK-1R antibody - Extracellular domain (AB219600)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NK-1R antibody - Extracellular domain (AB219600)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human lung adenocarcinoma tissue labeling NK-1R with ab219600 at 4 μg/mL.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NK-1R antibody - Extracellular domain (AB219600)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NK-1R antibody - Extracellular domain (AB219600)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain neuron tissue labeling NK-1R with ab219600 at 4 μg/mL.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human TACR1. The exact immunogen used to generate this antibody is proprietary information.

P25103

Specificity

BLAST analysis of the peptide immunogen showed no homology with other human proteins.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "2-4 µg/mL", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Dog": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Monkey": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rabbit": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.099% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is : substance P > substance K > neuromedin-K.
See full target information TACR1
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 12:e2404835 PubMed39985258

2025

A Silk Fibroin Nanoparticle Hydrogel Loaded With NK1R Antagonist Has Synergistic Anti-Inflammatory and Reparative Effects on Dry Eye Disease.

Applications

Unspecified application

Species

Unspecified reactive species

Bo Gong,Yi Liu,Huan Li,Xueming Ju,Dongfeng Li,Yuhao Zou,Xiaoxin Guo,Kai Dong,Jialing Xiao,Weijia Wu,Renjie Chai,Ruifan Zhang,Man Yu

Disease models & mechanisms 17: PubMed38415925

2024

Smad4 restricts injury-provoked biliary proliferation and carcinogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

William B Alexander,Wenjia Wang,Margaret A Hill,Michael R O'Dell,Luis I Ruffolo,Bing Guo,Katherine M Jackson,Nicholas Ullman,Scott C Friedland,Matthew N McCall,Ankit Patel,Nathania Figueroa-Guilliani,Mary Georger,Brian A Belt,Christa L Whitney-Miller,David C Linehan,Patrick J Murphy,Aram F Hezel

BMC cancer 23:158 PubMed36797689

2023

Expression of substance P, neurokinin 1 receptor, Ki-67 and pyruvate kinase M2 in hormone receptor negative breast cancer and evaluation of impact on overall survival.

Applications

Unspecified application

Species

Unspecified reactive species

Maha S Al-Keilani,Roba Bdeir,Rana I Elstaty,Mohammad A Alqudah

International journal of breast cancer 2022:4987912 PubMed35419208

2022

The Prognostic Potential of Neurokinin 1 Receptor in Breast Cancer and Its Relationship with Ki-67 Index.

Applications

Unspecified application

Species

Unspecified reactive species

Maha S Al-Keilani,Rana Elstaty,Mohammad A Alqudah
View all publications
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