Rabbit Polyclonal NMES1 antibody. Suitable for IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human NMES1 aa 1 to C-terminus.
View Alternative Names
C15orf48, NMES1, Normal mucosa of esophagus-specific gene 1 protein, Protein FOAP-11
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NMES1 antibody (AB272562)
Paraffin-embedded formalin-fixed Human colon tissue stained for NMES1 using ab272562 at 1/200 in immunohistochemical analysis.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NMES1 antibody (AB272562)
Paraffin-embedded formalin-fixed Human liver tissue stained for NMES1 using ab272562 at 1/200 in immunohistochemical analysis. No positivity in hepatocytes as expected.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NMES1 antibody (AB272562)
Paraffin-embedded formalin-fixed Human rectum tissue stained for NMES1 using ab272562 at 1/200 in immunohistochemical analysis.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NMES1 antibody (AB272562)
Paraffin-embedded formalin-fixed Human pancreas tissue stained for NMES1 using ab272562 at 1/200 in immunohistochemical analysis.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NMES1 antibody (AB272562)
Paraffin-embedded formalin-fixed Human testis tissue stained for NMES1 using ab272562 at 1/200 in immunohistochemical analysis.
Reactivity data
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Supplementary information
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Biological function summary
NMES1 influences cellular structure and organization. While it does not typically exist as part of large protein complexes its role in cytoskeletal interactions places it at the core of cellular stability mechanisms. NMES1 interacts with microtubules and actin filaments underpinning the cellular framework essential for muscle contraction and mechanical stress response. These interactions highlight its potential role in cellular processes beyond simple structural support.
Pathways
NMES1 involvement centers on cytoskeletal regulation and muscle contraction processes. It plays a part in the actin cytoskeleton signaling pathway where it interacts with proteins like actin-binding molecules that modulate cellular tension and motility. Additionally NMES1 has connections with muscle-specific signaling pathways like the myogenesis pathway suggesting its participation in muscle cell differentiation and growth. Through these interactions it supports the integration of mechanical signals into biological responses.
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