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AB250989

Anti-NSG2 antibody [EPR15389(B)] - BSA and Azide free

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Rabbit Recombinant Monoclonal NSG2 antibody. Carrier free. Suitable for WB and reacts with Mouse, Human, Rat samples.

View Alternative Names

CALY3, NSG2, Neuronal vesicle trafficking-associated protein 2, Neuron-specific protein family member 2, Protein p19, Hmp19

2 Images
Western blot - Anti-NSG2 antibody [EPR15389(B)] - BSA and Azide free (AB250989)
  • WB

Supplier Data

Western blot - Anti-NSG2 antibody [EPR15389(B)] - BSA and Azide free (AB250989)

This data was developed using ab189513, the same antibody clone in a different buffer formulation.

All lanes:

Western blot - Anti-NSG2 antibody [EPR15389(B)] - BSA and Azide free (ab250989) at 1/1000 dilution

Lane 1:

SH-SY5Y cell lysate at 10 µg

Lane 2:

Rat brain lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 19 kDa

false

Western blot - Anti-NSG2 antibody [EPR15389(B)] - BSA and Azide free (AB250989)
  • WB

Supplier Data

Western blot - Anti-NSG2 antibody [EPR15389(B)] - BSA and Azide free (AB250989)

This data was developed using ab189513, the same antibody clone in a different buffer formulation.

All lanes:

Western blot - Anti-NSG2 antibody [EPR15389(B)] - BSA and Azide free (ab250989) at 1/1000 dilution

Lane 1:

Neuro-2a cell lysate at 20 µg

Lane 2:

Human fetal brain lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 19 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR15389(B)

Isotype

IgG

Carrier free

Yes

Reacts with

Mouse, Rat, Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

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Product details

ab250989 is the carrier-free version of ab189513.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

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Properties and storage information

Form
Liquid
Storage buffer
pH: 7.2 - 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

NSG2 also known as Neuronal Vesicle Trafficking Associated 2 is a protein involved in intracellular processes. It has a molecular mass of approximately 49 kDa. NSG2 predominantly expresses in the brain particularly in neurons which suggests its critical role in neural activity. The protein localizes in synaptic vesicles hinting at its involvement in synaptic functions. Its expression is tightly regulated during neuronal development indicating its potential role in neural differentiation and maturation.
Biological function summary

The NSG2 protein contributes to vesicle trafficking within neuronal cells. It plays a part in a multiprotein complex that may regulate synaptic vesicle cycling or neurotransmitter release. The protein influences synaptic structure and function important for neural communication. Researchers have observed its significant impact on maintaining synaptic plasticity suggesting its role in learning and memory processes.

Pathways

NSG2 participates in neural development and synaptic communication pathways. It interacts within the neurotransmitter release cycle specifically affecting the synaptic vesicle cycle. In this context proteins such as SNAP-25 and synaptotagmin may have close interactions with NSG2 through these pathways. These interactions highlight the significance of NSG2 in neural circuit stability and function impacting neuronal transmission efficiency.

NSG2 has associations with neurological conditions including autism spectrum disorder and schizophrenia. Altered expression or mutation of NSG2 links it with these cognitive and developmental disorders. The protein's interactions with other targets like SNAP-25 and synaptotagmin might play a part in the manifestation or progression of these conditions. Understanding NSG2's role in these disorders could contribute to the development of therapeutic strategies.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information NSG2
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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