AB233079

Anti-NUP155 antibody

Name: Anti-NUP155 antibody (ab233079) | Abcam
Brand: Abcam Limited
SKU: AB233079

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(1 Publication)

Rabbit Polyclonal NUP155 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human NUP155 aa 1150 to C-terminus.

View Alternative Names

KIAA0791, NUP155, Nuclear pore complex protein Nup155, 155 kDa nucleoporin, Nucleoporin Nup155

6 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NUP155 antibody (AB233079)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NUP155 antibody (AB233079)

Formalin-fixed, paraffin-embedded human prostate tissue stained for NUP155 using ab233079 at 20 μg/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NUP155 antibody (AB233079)

Paraffin-embedded human glioma tissue stained for NUP155 using ab233079 at 20 μg/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NUP155 antibody (AB233079)

Paraffin-embedded human colon tissue stained for NUP155 using ab233079 at 20 μg/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NUP155 antibody (AB233079)

Paraffin-embedded human kidney tissue stained for NUP155 using ab233079 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Supplier Data

Western blot - Anti-NUP155 antibody (AB233079)

All lanes:

Western blot - Anti-NUP155 antibody (ab233079) at 3 µg/mL

All lanes:

Recombinant human NUP155 protein

Secondary

All lanes:

HRP-Linked Guinea pig Anti-Rabbit at 1/2000 dilution

Predicted band size: 155 kDa

false

Supplier Data

Western blot - Anti-NUP155 antibody (AB233079)

All lanes:

Western blot - Anti-NUP155 antibody (ab233079) at 3 µg/mL

Lane 1:

HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate

Lane 2:

HeLa (human epithelial cell line from cervix adenocarcinoma) cell lysate

Lane 3:

Jurkat (human T cell leukemia cell line from peripheral blood) cell lysate

Secondary

All lanes:

HRP-Linked Guinea pig Anti-Rabbit Ab at 1/2000 dilution

Predicted band size: 155 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human NUP155 aa 1150 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

O75694

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

ab233079 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.

Storage buffer

pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

NUP155 is a nucleoporin a component of the nuclear pore complex that regulates nucleocytoplasmic transport. Its mass is approximately 155 kDa. The protein is prominently expressed in tissues with high cellular activity like the liver and pancreas as it assists in managing the transport needs of these metabolically active areas. NUP155 facilitates the exchange of molecules between the nucleus and the cytoplasm playing a significant role in cellular communication.

Biological function summary

This nucleoporin is essential in maintaining the structure and function of the nuclear envelope. NUP155 is part of the extensive nuclear pore complex which consists of multiple proteins working together to manage the transport of RNA and proteins across the nuclear envelope. NUP155 acts as a scaffold that helps maintain the integrity of this complex ensuring the proper exchange between nuclear and cytoplasmic compartments vital for gene regulation and expression.

Pathways

NUP155 participates in pathways like nucleocytoplasmic transport and cell cycle regulation. It interacts with other nuclear pore proteins such as NUP93 and NUP205 to coordinate the import and export of macromolecules. In the cell cycle pathway NUP155 ensures proper mitotic progression by managing the transport of regulatory proteins necessary for cell division.

Alterations in NUP155 function have associations with cardiac arrhythmias and certain types of cancers. In arrhythmias NUP155 mutations disrupt cellular signaling processes affecting cardiac rhythm regulation. Linked with tumorigenesis abnormal NUP155 expression can alter nucleocytoplasmic transport contributing to cancer development. Its interactions with other proteins like NUP93 may offer insights into therapeutic targets for these conditions.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.

See full target information NUP155

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of biological chemistry 300:105502 PubMed38016515

2023

Fatty acids and inflammatory stimuli induce expression of long-chain acyl-CoA synthetase 1 to promote lipid remodeling in diabetic kidney disease.

Applications

Unspecified application

Species

Unspecified reactive species

Chih-Hong Wang, Surbhi,Sayhaan Goraya,Jaeman Byun,Subramaniam Pennathur

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-NUP155 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NUP155 antibody (AB233079)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NUP155 antibody (AB233079)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NUP155 antibody (AB233079)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NUP155 antibody (AB233079)

Western blot - Anti-NUP155 antibody (AB233079)

Western blot - Anti-NUP155 antibody (AB233079)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

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