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Rabbit Recombinant Monoclonal NUP155 antibody. Carrier free. Suitable for ICC/IF, WB, Flow Cyt (Intra) and reacts with Human samples.

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Images

Western blot - Anti-NUP155 antibody [EPR17111] - BSA and Azide free (AB251277), expandable thumbnail
  • Immunocytochemistry/ Immunofluorescence - Anti-NUP155 antibody [EPR17111] - BSA and Azide free (AB251277), expandable thumbnail
  • Flow Cytometry (Intracellular) - Anti-NUP155 antibody [EPR17111] - BSA and Azide free (AB251277), expandable thumbnail
  • Western blot - Anti-NUP155 antibody [EPR17111] - BSA and Azide free (AB251277), expandable thumbnail
  • Western blot - Anti-NUP155 antibody [EPR17111] - BSA and Azide free (AB251277), expandable thumbnail

Key facts

Isotype
IgG
Host species
Rabbit
Storage buffer

pH: 7.2 - 7.4
Constituents: PBS

Form
Liquid
Clonality
Monoclonal

Immunogen

  • The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
ICC/IFWBFlow Cyt (Intra)
Human
Tested
Tested
Tested

Tested
Tested

Species
Human
Dilution info
-
Notes

-

Tested
Tested

Species
Human
Dilution info
-
Notes

-

Tested
Tested

Species
Human
Dilution info
-
Notes

-

Target data

Function

Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.

Alternative names

KIAA0791, NUP155, Nuclear pore complex protein Nup155, 155 kDa nucleoporin, Nucleoporin Nup155

Recommended products

Rabbit Recombinant Monoclonal NUP155 antibody. Carrier free. Suitable for ICC/IF, WB, Flow Cyt (Intra) and reacts with Human samples.

Key facts

Isotype
IgG
Form
Liquid
Clonality
Monoclonal
Immunogen
  • The exact immunogen used to generate this antibody is proprietary information.
Carrier free
Yes
Clone number
EPR17111
Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze

Notes

ab251277 is the carrier-free version of Anti-NUP155 antibody [EPR17111] ab199528.

Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. The carrier-free buffer and high concentration allow for increased conjugation efficiency.

This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.
Activity summary

NUP155 is a nucleoporin a component of the nuclear pore complex that regulates nucleocytoplasmic transport. Its mass is approximately 155 kDa. The protein is prominently expressed in tissues with high cellular activity like the liver and pancreas as it assists in managing the transport needs of these metabolically active areas. NUP155 facilitates the exchange of molecules between the nucleus and the cytoplasm playing a significant role in cellular communication.

Biological function summary

This nucleoporin is essential in maintaining the structure and function of the nuclear envelope. NUP155 is part of the extensive nuclear pore complex which consists of multiple proteins working together to manage the transport of RNA and proteins across the nuclear envelope. NUP155 acts as a scaffold that helps maintain the integrity of this complex ensuring the proper exchange between nuclear and cytoplasmic compartments vital for gene regulation and expression.

Pathways

NUP155 participates in pathways like nucleocytoplasmic transport and cell cycle regulation. It interacts with other nuclear pore proteins such as NUP93 and NUP205 to coordinate the import and export of macromolecules. In the cell cycle pathway NUP155 ensures proper mitotic progression by managing the transport of regulatory proteins necessary for cell division.

Associated diseases and disorders

Alterations in NUP155 function have associations with cardiac arrhythmias and certain types of cancers. In arrhythmias NUP155 mutations disrupt cellular signaling processes affecting cardiac rhythm regulation. Linked with tumorigenesis abnormal NUP155 expression can alter nucleocytoplasmic transport contributing to cancer development. Its interactions with other proteins like NUP93 may offer insights into therapeutic targets for these conditions.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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