Anti-NUP88 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

NUP88 serves as an important component of the nuclear pore complex which is responsible for maintaining communication between the nucleus and cytoplasm. The protein forms part of an extensive network known as the nuclear pore complex allowing regulated transport. NUP88 interacts closely with other nucleoporins such as NUP214 to maintain the structural integrity of the nuclear pore and ensure proper cellular function. It has been implicated in the transport of specific cargo molecules that maintain homeostasis within the cell.

Pathways

NUP88 engages in the nuclear transport pathway playing a critical role in the direction of nuclear import and export processes. This pathway is essential for proper gene expression and cell cycle regulation. In the context of nuclear transport NUP88 works with proteins like importins and exportins to facilitate the movement of signaling molecules that drive these processes. Another significant pathway involving NUP88 is the immune response pathway where it helps mediate the transport of interferon-induced proteins.