JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB118565

Anti-OCIAD2 antibody

Be the first to review this product! Submit a review

|

(3 Publications)

Rabbit Polyclonal OCIAD2 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human OCIAD2 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

OCIA domain-containing protein 2, Ovarian carcinoma immunoreactive antigen-like protein, OCIAD2

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OCIAD2 antibody (AB118565)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OCIAD2 antibody (AB118565)

ab118565, at 5 µg/ml, staining OCIAD2 in Formalin-fixed, Paraffin-embedded Human Kidney tissue by Immunohistochemistry.

Western blot - Anti-OCIAD2 antibody (AB118565)
  • WB

Unknown

Western blot - Anti-OCIAD2 antibody (AB118565)

Lane 1:

Western blot - Anti-OCIAD2 antibody (ab118565) at 0.5 µg/mL

Lane 2:

Western blot - Anti-OCIAD2 antibody (ab118565) at 1 µg/mL

All lanes:

SK N SH cell lysate

Predicted band size: 17 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Synthetic Peptide within Human OCIAD2 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q56VL3

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-1 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5 µg/mL", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

OCIAD2 also known as ovarian cancer immunoreactive antigen domain containing 2 is a protein found in humans. It has a molecular mass of approximately 29 kDa. OCIAD2 is expressed in various tissues including the ovary breast and kidney. It localizes mainly in the cytoplasm and mitochondria suggesting a role in cellular processes related to these organelles.
Biological function summary

OCIAD2 impacts cellular processes through its involvement in cell differentiation and cellular stress responses. It may associate with multiprotein complexes that regulate these functions. Studies indicate OCIAD2 interacts with mitochondrial outer membrane components which hints it might play a role in mitochondrial dynamics. Through these interactions OCIAD2 contributes to maintaining cellular homeostasis during stress.

Pathways

OCIAD2 participates in pathways like oxidative phosphorylation and apoptosis. These pathways are important for cellular energy production and programmed cell death. OCIAD2 may interact with proteins such as cytochrome c and members of the Bcl-2 family in these processes. Through its involvement OCIAD2 helps regulate energy balance and cell survival influencing the fate of cells under various stimuli.

OCIAD2 has a connection to ovarian cancer and breast cancer. Abnormal expression of OCIAD2 associates with tumor progression and poor prognosis in ovarian cancer. In this context OCIAD2 might work with proteins like BRCA1 and HER2 which are critical in cancer biology. Understanding OCIAD2's role in these cancers could lead to potential therapeutic strategies or biomarkers for diagnosis.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information OCIAD2
style
left-column

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Biomolecules & biomedicine 25:940-953 PubMed39466086

2024

Hsa_circ_0001492 regulates the hsa-miR-145-5p/ovarian carcinoma immunoreactive antigen domain 2 axis to promote the progression of lung adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yuanqiang He,Gang Li,Ran Fu,Yue Li,Ying Wang

Frontiers in pharmacology 13:777612 PubMed35295342

2022

The SKA3-DUSP2 Axis Promotes Gastric Cancer Tumorigenesis and Epithelial-Mesenchymal Transition by Activating the MAPK/ERK Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Chao Zhang,Shutao Zhao,Yuen Tan,Siwei Pan,Wen An,Qingchuan Chen,Xudong Wang,Huimian Xu

Annals of translational medicine 8:1670 PubMed33490182

2021

Proteomics and metabolomics of raw rhubarb and wine-processed rhubarb in the treatment of rats with intracerebral hemorrhage.

Applications

Unspecified application

Species

Unspecified reactive species

Kun Wang,Dongsheng Guan,Xu Zhao,Dongge Qiao,Yanhua Yang,Yinglin Cui
View all publications
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB204493

Anti-AIF1L antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AIF1L antibody (AB204493)

  • 0
  • 0
Primary Antibodies

AB137060

Anti-Amino-terminal enhancer of split/AES antibody [EPR8385]

RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-Amino-terminal enhancer of split/AES antibody [EPR8385] (AB137060)

  • 0
  • 0
Primary Antibodies

AB47252

Anti-SPANX antibody

Western blot - Anti-SPANX antibody (AB47252)

  • 0
  • 0
Primary Antibodies

AB118894

Anti-SCARA5 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SCARA5 antibody (AB118894)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com