Anti-Okadaic Acid antibody [7E1]

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Okadaic acid inhibits protein phosphatases by binding directly to their catalytic subunits preventing dephosphorylation of proteins. This inhibition affects multiple cell signaling pathways causing disruptions in normal cellular processes. Okadaic acid is not typically part of a complex but interacts directly with its targets in its active form to exert its effects. It influences processes such as cell cycle progression apoptosis and inflammation making it a valuable tool for studying cellular regulation.

Pathways

Okadaic acid influences key cell signaling pathways like the Wnt signaling pathway and the cell cycle regulation pathway. In the Wnt pathway it modulates the stability of beta-catenin impacting gene expression and cell fate decisions. In cell cycle regulation okadaic acid affects the activity of cyclin-dependent kinases (CDKs) by altering their phosphorylation state thereby influencing cell division cycles.