AB190792

Anti-OLF1 antibody [EPR15972]

RabMAb
Recombinant
What is this?

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(1 Publication)

Rabbit Recombinant Monoclonal OLF1 antibody. Suitable for WB and reacts with Mouse, Rat, Human samples. Cited in 1 publication.

View Alternative Names

OLF1, OR5I1, Olfactory receptor 5I1, Olfactory receptor OR11-159, Olfactory receptor-like protein OLF1

2 Images

Supplier Data

Western blot - Anti-OLF1 antibody [EPR15972] (AB190792)

All lanes:

Western blot - Anti-OLF1 antibody [EPR15972] (ab190792) at 1/10000 dilution

Lane 1:

Human fetal brain lysate at 20 µg

Lane 2:

Human fetal heart lysate at 20 µg

Lane 3:

HepG2 cell lysate at 20 µg

Lane 4:

Jurkat cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 36 kDa

Observed band size: 36 kDa

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Supplier Data

Western blot - Anti-OLF1 antibody [EPR15972] (AB190792)

All lanes:

Western blot - Anti-OLF1 antibody [EPR15972] (ab190792) at 1/1000 dilution

Lane 1:

Mouse brain lysate at 10 µg

Lane 2:

Mouse heart lysate at 10 µg

Lane 3:

Mouse kidney lysate at 10 µg

Lane 4:

Mouse spleen lysate at 10 µg

Lane 5:

Rat brain lysate at 10 µg

Lane 6:

Rat heart lysate at 10 µg

Lane 7:

Rat kidney lysate at 10 µg

Lane 8:

Rat spleen lysate at 10 µg

Lane 9:

C6 cell lysate at 10 µg

Lane 10:

Raw264.7 cell lysate at 10 µg

Lane 11:

PC12 cell lysate at 10 µg

Lane 12:

NIH3T3 cell lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 36 kDa

Observed band size: 36 kDa

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Carrier free

Anti-OLF1 antibody [EPR15972] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR15972

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "" } } }

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Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

OLF1 also known as OLF-1-like protein or Olfactory neuron specific factor 1 functions mainly as a transcription factor. It weighs approximately 34 kDa and is primarily expressed in neurons and tissues related to the olfactory system. OLF1 binds specific DNA sequences to regulate the transcription of genes involved in olfactory receptor expression. It plays a critical role in the development and function of the olfactory system by influencing gene networks specific to olfactory receptors.

Biological function summary

OLF1 impacts the expression of olfactory receptor genes by interacting with other transcription factors within the nucleus. It functions as part of larger transcriptional complexes to modulate olfactory receptor gene expression. Through these activities OLF1 contributes significantly to the regulation of sensory perception in mammals. Its precise role in olfactory development and sensory neuron identity highlights its importance in neural biology.

Pathways

OLF1 is integrated into the olfactory signaling pathway. It cooperates with proteins like O/E-1 and O/E-3 to regulate olfactory receptor gene clusters. This regulation is important for odor detection and signal transduction in the olfactory pathway. The olfactory signaling pathway involves multiple stages including ligand binding and signal transduction in which OLF1 contributes through its transcriptional regulatory functions.

Alterations in OLF1 activity have been linked to anosmia a condition characterized by the loss of smell. Researchers also explore its involvement in neurodegenerative disorders where olfactory deficits are early symptoms such as Parkinson’s disease. Examining OLF1 interactions with proteins such as alpha-synuclein provides insights into its potential role in the pathogenesis of these conditions.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Odorant receptor.

See full target information OR5I1

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Epigenetics 20:2498859 PubMed40296586

2025

Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy loss.

Applications

Unspecified application

Species

Unspecified reactive species

Delna Irani,Deepshikha Arya,Deepti Tandon,Vandana Bansal,Anushree Patil,Dipty Singh

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-OLF1 antibody [EPR15972]

Western blot - Anti-OLF1 antibody [EPR15972] (AB190792)

Western blot - Anti-OLF1 antibody [EPR15972] (AB190792)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

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