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AB223118

Anti-ompK antibody

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(1 Publication)

Rabbit Polyclonal OMPK antibody. Suitable for WB and reacts with Recombinant full length protein - Vibrio parahaemolyticus samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Vibrio parahaemolyticus RIMD 2210633 ompK.

View Alternative Names

VP2362, ompK, Outer membrane protein OmpK

1 Images
Western blot - Anti-ompK antibody (AB223118)
  • WB

Supplier Data

Western blot - Anti-ompK antibody (AB223118)

All lanes:

Western blot - Anti-ompK antibody (ab223118) at 1/500 dilution

Lane 1:

Recombinant ompK protein at 0.06 µg

Lane 2:

Recombinant ompK protein at 0.03 µg

Lane 3:

Recombinant ompK protein at 0.015 µg

Lane 4:

Recombinant ompK protein at 0.0075 µg

Secondary

All lanes:

Goat polyclonal to rabbit IgG at 1/50000 dilution

Predicted band size: 30 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Vibrio parahaemolyticus

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Vibrio parahaemolyticus RIMD 2210633 ompK.

P59570

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  • 0
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Primary Antibodies

AB183947

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  • 4
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Primary Antibodies

AB69617

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Proteins & Peptides

AB274664

Recombinant Chlamydia trachomatis MOMP protein

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  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Recombinant full length protein - Vibrio parahaemolyticus": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>" }, "Vibrio parahaemolyticus": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity >95%.
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The protein OmpK also known as outer membrane protein K functions as a porin channel in Gram-negative bacteria. This protein facilitates the passive diffusion of small molecules across the bacterial outer membrane contributing to nutrient uptake and waste elimination. OmpK holds a molecular mass of approximately 36 kDa. You typically find it expressed in the outer membrane of bacteria such as Klebsiella pneumoniae. It forms β-barrel structures that allow solute transport across the membrane.
Biological function summary

Outer membrane protein K plays a role in bacterial virulence and antibiotic resistance. OmpK works within a complex structure to maintain membrane integrity and respond to environmental changes. Its ability to form channels in the cell wall assists in balancing osmotic pressure and mediating interactions with the host. Alterations in its expression or structure can influence antibiotic susceptibility and the ability of the bacteria to cause disease.

Pathways

Outer membrane protein K functions importantly in the bacterial metabolism and resistance pathways. It participates in the nutrient uptake pathway which is essential for bacterial survival and growth. OmpK interacts with other outer membrane proteins such as OmpA to modulate membrane permeability. It can also be involved in pathways related to the bacterial stress response adapting to environmental pressures like antibiotic presence.

Outer membrane protein K associates with infections caused by Klebsiella pneumoniae including pneumonia and urinary tract infections. Changes in OmpK expression can lead to multidrug-resistant strains complicating treatment options. OmpK is interconnected with efflux pump proteins like AcrAB-TolC contributing to antibiotic resistance mechanisms. Understanding these connections highlights the significance of OmpK in combating bacterial infections and developing treatment strategies.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Serves as receptor for a broad-host-range vibriophage, KVP40.
See full target information ompK
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of cellular and molecular medicine 23:1541-1552 PubMed30597727

2018

MiR-552 promotes the proliferation, migration and EMT of hepatocellular carcinoma cells by inhibiting AJAP1 expression.

Applications

Unspecified application

Species

Unspecified reactive species

Weiqing Qu,Xinyuan Wen,Keli Su,Wei Gou
View all publications
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Product promise

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