Anti-Opn1mw antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Cone photoreceptor cells use Opn1mw to detect and respond to specific wavelengths of light which is essential for proper color vision. Opn1mw forms part of the phototransduction complex which converts photon absorption into electrical signals interpreted by the brain as vision. This conversion process involves changes in the conformation of the opsin protein leading to a cascade of intracellular events that ultimately result in a nerve impulse. Without the proper function of this protein the capacity to distinguish medium-wavelength colors would be impaired.

Pathways

Opn1mw interacts with the phototransduction pathway an intricate signal transduction pathway essential for vision. This pathway involves several other proteins such as transducin and phosphodiesterase which help propagate the electrical signal initiated by light absorption by Opn1mw. Another significant interaction is with the cGMP pathway where cGMP levels decrease in response to the activation of Opn1mw leading to hyperpolarization of the photoreceptor cell membrane.