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AB129895

Anti-OR10AD1 antibody

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(1 Publication)

Rabbit Polyclonal OR10AD1 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human OR10AD1.

View Alternative Names

OR10AD1P, OR10AD1, Olfactory receptor 10AD1, Olfactory receptor OR12-1

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-OR10AD1 antibody (AB129895)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-OR10AD1 antibody (AB129895)

ab129895, at 1/100 dilution, staining OR10AD1 in A549 cells by Immunofluorescence, in the presence (right panel) or absence (left panel) of immunizing peptide.

Western blot - Anti-OR10AD1 antibody (AB129895)
  • WB

Unknown

Western blot - Anti-OR10AD1 antibody (AB129895)

All lanes:

Western blot - Anti-OR10AD1 antibody (ab129895) at 1/500 dilution

Lane 1:

HeLa cell extract

Lane 2:

HeLa cell extract with immunizing peptide

Predicted band size: 36 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

Synthetic Peptide within Human OR10AD1. The exact immunogen used to generate this antibody is proprietary information.

Q8NGE0

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/500", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Stable for 12 months at -20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

OR10AD1 also known as Olfactory Receptor 10AD1 is a G-protein coupled receptor involved in olfactory signal transduction. It has a molecular mass of approximately 34 kDa. This olfactory receptor is expressed in the sensory neurons of the olfactory epithelium. OR10AD1 contributes to detecting specific odorant molecules helping to initiate smell perception.
Biological function summary

The olfactory receptor 10AD1 contributes to the detection of chemical stimuli necessary for olfactory perception. It forms part of a vast family of olfactory receptors which work collectively to identify a wide range of odorant molecules. It has a role in a sophisticated system that helps animals recognize food predators and mating partners based on scent.

Pathways

The olfactory transduction pathway involves OR10AD1 translating external chemical signals into neuronal responses. This receptor associates with the G-protein olfactory transduction cascade where it activates adenylate cyclase leading to the production of cAMP. It might relate to other olfactory receptors such as those activating similar signaling molecules like AC3 facilitating the detection of diverse odorants.

Researchers have not extensively linked OR10AD1 to specific pathologies. However olfactory receptors in general have potential implications in conditions like anosmia or the loss of smell which can affect the quality of life. Some studies explore their roles in neurological diseases due to their expression in brain regions beyond the olfactory epithelium where OR10AD1 could interact with other proteins like OMP (Olfactory Marker Protein).
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Odorant receptor.
See full target information OR10AD1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of cellular and molecular medicine 28:e18366 PubMed38856956

2024

Overexpression of olfactory receptor 78 ameliorates brain injury in cerebral ischaemia-reperfusion rats by activating Prkaca-mediated cAMP/PKA-MAPK pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Tao Kang,Lijuan Zhu,Yanli Xue,Qian Yang,Qi Lei,Qianqian Wang
View all publications
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