Organelle markers

Define the subcellular landscape of your samples with a comprehensive range of organelle markers for the nuclei, mitochondria, ER, and more. Part of a world-leading portfolio of over 60k primary antibodies with over 600k citations, these validated antibodies provide the precise spatial context required to map protein localization with total confidence.

What is an organelle marker antibody?

A eukaryotic cell is composed of membrane-bound organelles. Each organelle contains different proteins and has a different role to play in the functioning of the cell. Organelle marker antibodies are used to identify and study specific components/proteins of organelles and explore protein localization in situ.

When should I use an organelle marker antibody?

When using marker antibodies, researchers often have an interest in confirming the subcellular location of target proteins and other proteins to understand their function to gain insights into cellular processes and disease mechanisms.

Immunofluorescence and western blotting are common techniques for these studies. The importance of antibody specificity and the need to validate targets are essential to ensure reliable results.

Visualization techniques such as immunofluorescence enable detailed study of organelle structure and protein distribution.

Co localization studies using immunofluorescence can reveal spatial relationships between different organelle markers.

Live cell imaging and the use of HeLa cells have advanced the study of protein localization and organelle dynamics.

Organelle marker antibodies can also be used to detect alterations in protein localization, which may indicate changes in cellular processes or disease states.