Intercellular junction markers

Explore the structural integrity of tissue barriers with our validated antibodies for intercellular junctions, including ZO-1 for tight junctions, E-cadherin for adherens junctions, and Desmoglein. Part of a range of over 60k primary antibodies with over 600k citations, these markers provide the high-affinity binding required to study cell-cell communication, epithelial-to-mesenchymal transition (EMT), and barrier function in both health and disease.

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What is the intercellular junction?

Intercellular junctions are specialized structures that connect adjacent cells, maintaining tissue integrity and enabling communication. They include tight junctions, adherens junctions, desmosomes, and gap junctions, each serving distinct roles in controlling permeability, mechanical stability, and signal exchange between cells. These junctions are especially important in epithelial and endothelial tissues.

What are intercellular junction markers used to study?

Intercellular junction markers are used to study cell adhesion, barrier function, and tissue organization. Common markers like ZO-1 (tight junctions), E-cadherin (adherens junctions), and connexins (gap junctions) help researchers investigate processes such as development, wound healing, cancer metastasis, and inflammatory responses.