Anti-Orthoreovirus fusion protein p10 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Orthoreovirus p10 fusion protein assists in mediating the formation of syncytia which are large multinucleated cells resulting from fusion. This function suggests that p10 is part of a larger fusogenic complex involving other viral proteins and host cell components. p10 curves the host cell membrane during the fusion process which further aids in the merging of viral and cellular membranes. This activity highlights its role in viral pathogenic mechanisms.

Pathways

Orthoreovirus p10 interacts with host cell signaling pathways involved in membrane rearrangement and immune responses. It interferes with normal metabolical functions to promote viral replication and spread. p10 protein's activity is associated with pathways related to membrane trafficking and reorganization working alongside proteins like orthoreovirus p14 and other viral fusogenic proteins. These interactions emphasize the protein's significance in viral infection pathways.