Anti-OTOP2 antibody [EPR9484] - BSA and Azide free

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

The protein OTOP2 also known as Otopetrin 2 is involved in proton channel activity. It has an approximate molecular mass of 70 kDa. OTOP2 expresses in various tissues including the vestibular system and other sensory organs. Its role involves contributing to chemical gradients helping with cellular processes within these systems. This expression pattern points to its relevance in sensory functions mainly in maintaining balance and spatial orientation.

Biological function summary

OTOP2 influences ion balance in cells. This protein participates in cellular activities by modulating pH and ionic concentrations. OTOP2 often functions on its own without being part of larger protein complexes to achieve its regulatory roles. Its activity ensures cells maintain an environment that supports normal cellular operations and signaling particularly in response to external stimuli.

Pathways

OTOP2 plays a role in ion transport and sensory perception pathways. It aligns with key proteins involved in sensory signaling such as OTOP1 and OTOP3 which participate in similar sensory activities. This association indicates that OTOP2 functions in the contribution to sensory signal transduction. The involvement in these pathways highlights its importance in the body's response to sensory input and environmental changes.

Associated diseases and disorders

OTOP2 connects to balance disorders like vestibular dysfunctions. Such conditions are due to the malfunction of sensory signaling related to balance. Proteins such as OTOP1 are similarly linked in these disorders emphasizing their collective importance in vestibular health. Additionally understanding how OTOP2 works can inform research into improved treatments for these conditions.