AB17293

Anti-Ovalbumin antibody [6C8]

Lab Essentials
What is this?

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(15 Publications)

Anti-Ovalbumin antibody [6C8] (ab17293) is a mouse monoclonal antibody detecting Ovalbumin in Western Blot, ELISA. Suitable for Chicken.

- Over 10 publications
- Trusted since 2005

View Alternative Names

Ovalbumin, Allergen Gal d II, Egg albumin, Plakalbumin, SERPINB14, OVA

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

6C8

Isotype

IgG1

Light chain type

kappa

Carrier free

Reacts with

Chicken

Applications

WB, ELISA

applications

Immunogen

Native Full Length Protein corresponding to Chicken SERPINB14.

P01012

Specificity

The antibody reacts strongly with Ovalbumin (OA) in denatured and modified forms (native OA surface-adsorbed, heat-denatured or reduced).Strong reaction is seen in ELISA, with OA directly coated onto the microtiterwell.In dotblotting it reacts with both native and denatured OA adsorbed onto nitrocellulose.In Western blotting after SDS-PAGE, the antibody reacts with OA in reduced as well as unreduced forms.

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Reactivity data

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Product details

What is this antibody validated in?
Anti-Ovalbumin antibody [6C8] (ab17293) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), ELISA in Chicken samples.

Trusted by the scientific community
Anti-Ovalbumin [6C8] (ab17293) was first used in a scientific publication in 2005 and has been cited over 10 times in peer-reviewed journals.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Purification notes

Immunized i.p. with immunogen adsorbed onto Al(OH)3.

Storage buffer

pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS, 2.9% Sodium chloride

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Ovalbumin also known as egg albumin is a significant protein found in egg white representing about 54% of the protein content in this part of the egg. It has a molecular weight of approximately 45 kDa. This protein is synthesized in the oviduct of birds and deposited in the egg white where it fulfills several roles. Ovalbumin is a glycoprotein meaning it has carbohydrate groups attached to the polypeptide chain. Researchers commonly use it as a model antigen in immunology studies and as a standard in protein markers because of its known properties.

Biological function summary

Ovalbumin functions as a storage protein in eggs providing essential amino acids for the developing embryo. This protein also plays a role in binding metal ions and vitamins acting as a nutrient reservoir. It is not part of a complex existing as a single polypeptide chain. Ovalbumin contributes to the regulation and transport of metabolic compounds due to its ability to bind ions. These properties make it useful in various biological studies and industrial applications.

Pathways

Four significant pathways involve the role of ovalbumin in living organisms. These include the regulation of protein adsorption and the nutrient reservoir activity pathway. Ovalbumin's ability to serve as a nutrient source directly relates to these pathways ensuring proper nourishment during embryo development. It operates independently of other proteins in these pathways emphasizing its role in providing and regulating nutrients without the aid of additional complexes.

Ovalbumin has connections to some allergic responses particularly in individuals with egg allergies. It acts as an allergen capable of provoking immune reactions. Ovalbumin lacks a direct connection to specific diseases beyond allergies. However understanding its interaction with immune system proteins like immunoglobulin E (IgE) is important as this is the primary mediator in allergic responses. This link makes ovalbumin important for research into allergy mechanisms and the development of hypoallergenic variants.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Non-inhibitory serpin. Storage protein of egg white.

See full target information SERPINB14

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Publications (15)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in immunology 15:1505971 PubMed39742275

2025

FB5P-seq-mAbs: monoclonal antibody production from FB5P-seq libraries for integrative single-cell analysis of B cells.

Applications

Unspecified application

Species

Unspecified reactive species

Sakina Ado,Chuang Dong,Noudjoud Attaf,Myriam Moussa,Agathe Carrier,Pierre Milpied,Jean-Marc Navarro

Science advances 10:eadq7006 PubMed39331702

2024

Systemic dysregulation and molecular insights into poor influenza vaccine response in the aging population.

Applications

Unspecified application

Species

Unspecified reactive species

Saumya Kumar,Martijn Zoodsma,Nhan Nguyen,Rodrigo Pedroso,Stephanie Trittel,Peggy Riese,Javier Botey-Bataller,Liang Zhou,Ahmed Alaswad,Haroon Arshad,Mihai G Netea,Cheng-Jian Xu,Frank Pessler,Carlos A Guzmán,Luis Graca,Yang Li

Journal of controlled release : official journal of the Controlled Release Society 374:550-562 PubMed39146981

2024

Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity.

Applications

Unspecified application

Species

Unspecified reactive species

Xin Luo,Kathleen M McAndrews,Kent A Arian,Sami J Morse,Viktoria Boeker,Shreyasee V Kumbhar,Yingying Hu,Krishnan K Mahadevan,Kaira A Church,Sriram Chitta,Nicolas T Ryujin,Janine Hensel,Jianli Dai,Dara P Dowlatshahi,Hikaru Sugimoto,Michelle L Kirtley,Valerie S LeBleu,Shabnam Shalapour,Joe H Simmons,Raghu Kalluri

Biomolecules 12: PubMed36008958

2022

Bioimprinting as a Receptor for Detection of Kwakhurin.

Applications

Unspecified application

Species

Unspecified reactive species

Seiichi Sakamoto,Kei Minami,Poomraphie Nuntawong,Gorawit Yusakul,Waraporn Putalun,Hiroyuki Tanaka,Shunsuke Fujii,Satoshi Morimoto

Journal of global health 12:05009 PubMed35265332

2022

Affordable IgY-based antiviral prophylaxis for resource-limited settings to address epidemic and pandemic risks.

Applications

Unspecified application

Species

Unspecified reactive species

Carrie J Chen,Anna F Hudson,Allison S Jia,Caitlin R Kunchur,Andrew J Song,Edward Tran,Chris J Fisher,Davide Zanchi,Lucia Lee,Stephen Kargotich,Mary Romeo,Ana Koperniku,Ravinder D Pamnani,Daria Mochly-Rosen

Cancer immunology research 10:126-141 PubMed34815265

2021

Plexin-A4 Mediates Cytotoxic T-cell Trafficking and Exclusion in Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Ward Celus,Ana I Oliveira,Silvia Rivis,Heleen H Van Acker,Ewout Landeloos,Jens Serneels,Sarah Trusso Cafarello,Yannick Van Herck,Roberta Mastrantonio,Arnaud Köhler,Abhishek D Garg,Véronique Flamand,Luca Tamagnone,Jean-Christophe Marine,Mario Di Matteo,Bruno M Costa,Oliver Bechter,Massimiliano Mazzone

Science signaling 14:eabc4764 PubMed34665642

2021

The injury response to DNA damage in live tumor cells promotes antitumor immunity.

Applications

Unspecified application

Species

Unspecified reactive species

Ganapathy Sriram,Lauren E Milling,Jung-Kuei Chen,Yi Wen Kong,Brian A Joughin,Wuhbet Abraham,Susanne Swartwout,Erika D Handly,Darrell J Irvine,Michael B Yaffe

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 50:231-243 PubMed31715648

2019

Chimeric specific antigen epitope-carrying dendritic cells induce interleukin-17(+) regulatory T cells to suppress food allergy.

Applications

Unspecified application

Species

Unspecified reactive species

Ling-Zhi Xu,Rui-Di Xie,Hai Xie,Ji-Yu Ju,Xiao-Yan Fu,Da-Lin Di,Mei-Yu Peng,Wei Gao,Yuan-Yi Zhang,Dian Yu,Jiang-Qi Liu,Gui Yang,Zhi-Qiang Liu,Zhi-Gang Liu,Ping-Chang Yang

Cell 176:1432-1446.e11 PubMed30827685

2019

Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA.

Applications

Unspecified application

Species

Unspecified reactive species

Katherine C Barnett,Julia M Coronas-Serna,Wen Zhou,Michael J Ernandes,Anh Cao,Philip J Kranzusch,Jonathan C Kagan

Immunology 149:157-71 PubMed27278624

2016

Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.

Applications

Species

Mouse

Yingping Xu,Yi Liu,Chunqing Yang,Li Kang,Meixiang Wang,Jingxia Hu,Hao He,Wengang Song,Hua Tang

View all publications

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