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Proteins and peptidesAnti-Ly6g antibody [1A8] - mouse IgG2c (Chimeric)
Low endotoxin, Azide free.
Our first-to-market chimera with mouse IgG2c backbone, this functional antibody specifically depletes neutrophils in vivo for up to 72h.
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Rabbit Polyclonal OVGP1/OGP antibody. Suitable for IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human OVGP1.
IgG
Rabbit
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 99% PBS
Liquid
Polyclonal
IHC-P | |
---|---|
Human | Tested |
Rat | Predicted |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 5 µg/mL | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Rat | Dilution info - | Notes - |
Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development.
Oviduct-specific glycoprotein, Estrogen-dependent oviduct protein, Mucin-9, Oviductal glycoprotein, Oviductin, OGP, MUC9, OVGP1
Rabbit Polyclonal OVGP1/OGP antibody. Suitable for IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human OVGP1.
Oviduct-specific glycoprotein, Estrogen-dependent oviduct protein, Mucin-9, Oviductal glycoprotein, Oviductin, OGP, MUC9, OVGP1
IgG
Rabbit
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 99% PBS
Liquid
Polyclonal
Synthetic Peptide within Human OVGP1. The exact immunogen used to generate this antibody is proprietary information.Database link Q12889
Affinity purification Immunogen
Blue Ice
1-2 weeks
+4°C
-20°C
Avoid freeze / thaw cycle
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
OVGP1 plays an important role in reproduction. It interacts with the zona pellucida and helps facilitate sperm binding and penetration enhancing fertilization potential. The protein is not part of a large complex but is known for modifying the environment in the oviduct to support fertility. It also maintains the stability and permeability of the oocyte and embryo matrix impacting early stages of embryo development.
OVGP1 also known as oviductal glycoprotein or OGP is a glycoprotein with a molecular mass around 120 kDa. This protein is expressed mainly in the oviduct epithelium in mammals. It is secreted during the peri-ovulatory phase and associates with the zona pellucida and the oocyte. OGP products are studied extensively due to their role in reproductive biology especially concerning fertilization and early embryonic development.
OVGP1 influences reproductive pathways that involve sperm-egg interaction and embryo transport. The glycoprotein acts along pathways connected to fertilization affecting the zona pellucida's structural and functional properties which are also influenced by proteins like ZP3 (zona pellucida glycoprotein 3). These pathways ensure that the conditions in the oviduct are optimal for successful conception and embryo support.
OVGP1 has been linked to infertility and reproductive challenges. Altered expression or dysfunction of this protein can affect fertility contributing to conditions like fallopian tube disorders and ectopic pregnancies. It might also interact with other proteins related to infertility such as inhibin affecting its pathways and mechanisms. Understanding these interactions provides insight into the treatment and management of reproductive health issues.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
ab118590, at 5 μg/ml, staining OVGP1/OGP in formalin fixed, paraffin embedded Human fallopian tube by Immunohistochemistry.
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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