Rabbit Polyclonal OVGP1/OGP antibody. Suitable for IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human OVGP1.
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Publications
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- Cytotechnology 74:531-5382022Long-term culture of feline oviduct epithelial cells on permeable filter supports.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSusanne Eder,Karin Müller,Shuai Chen,Jennifer SchoenPubMed 36238264
- Journal of medical primatology 47:362-3702018Hormonal regulation of oviductal glycoprotein 1 (OVGP1; MUC9) in the rhesus macaque cervix.Applications:Unspecified applicationReactive species:Unspecified reactive speciesOv Daniel Slayden et. al.PubMed 29971796
- Theriogenology 80:862-92013Long-term culture of primary porcine oviduct epithelial cells: validation of a comprehensive in vitro model for reproductive science.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShuai Chen et. al.PubMed 23973051
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human OVGP1. The exact immunogen used to generate this antibody is proprietary information. Database link Q12889
Reactivity data
Select an application| IHC-P | |
|---|---|
| Human | Tested |
| Rat | Predicted |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 5 µg/mL | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info - | Notes - |
Associated Products
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Target data
Function
Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development.
Alternative names
MUC9, OGP, OVGP1, Oviduct-specific glycoprotein, Estrogen-dependent oviduct protein, Mucin-9, Oviductal glycoprotein, Oviductin
Recommended products
Rabbit Polyclonal OVGP1/OGP antibody. Suitable for IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human OVGP1.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human OVGP1. The exact immunogen used to generate this antibody is proprietary information. Database link Q12889
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
OVGP1 also known as oviductal glycoprotein or OGP is a glycoprotein with a molecular mass around 120 kDa. This protein is expressed mainly in the oviduct epithelium in mammals. It is secreted during the peri-ovulatory phase and associates with the zona pellucida and the oocyte. OGP products are studied extensively due to their role in reproductive biology especially concerning fertilization and early embryonic development.
- Biological function summary
OVGP1 plays an important role in reproduction. It interacts with the zona pellucida and helps facilitate sperm binding and penetration enhancing fertilization potential. The protein is not part of a large complex but is known for modifying the environment in the oviduct to support fertility. It also maintains the stability and permeability of the oocyte and embryo matrix impacting early stages of embryo development.
- Pathways
OVGP1 influences reproductive pathways that involve sperm-egg interaction and embryo transport. The glycoprotein acts along pathways connected to fertilization affecting the zona pellucida's structural and functional properties which are also influenced by proteins like ZP3 (zona pellucida glycoprotein 3). These pathways ensure that the conditions in the oviduct are optimal for successful conception and embryo support.
- Associated diseases and disorders
OVGP1 has been linked to infertility and reproductive challenges. Altered expression or dysfunction of this protein can affect fertility contributing to conditions like fallopian tube disorders and ectopic pregnancies. It might also interact with other proteins related to infertility such as inhibin affecting its pathways and mechanisms. Understanding these interactions provides insight into the treatment and management of reproductive health issues.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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1 product image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OVGP1/OGP antibody (ab118590)
ab118590, at 5 μg/ml, staining OVGP1/OGP in formalin fixed, paraffin embedded Human fallopian tube by Immunohistochemistry.
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