AB118590

Anti-OVGP1/OGP antibody

Name: Anti-OVGP1/OGP antibody (ab118590) | Abcam
Brand: Abcam Limited
SKU: AB118590
Price: 630 USD
Availability: InStock
Rating: 4 (2 reviews)

(2 Reviews)

(6 Publications)

Rabbit Polyclonal OVGP1/OGP antibody. Suitable for IHC-P and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human OVGP1.

View Alternative Names

MUC9, OGP, OVGP1, Oviduct-specific glycoprotein, Estrogen-dependent oviduct protein, Mucin-9, Oviductal glycoprotein, Oviductin

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OVGP1/OGP antibody (AB118590)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OVGP1/OGP antibody (AB118590)

ab118590, at 5 μg/ml, staining OVGP1/OGP in formalin fixed, paraffin embedded Human fallopian tube by Immunohistochemistry.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human OVGP1. The exact immunogen used to generate this antibody is proprietary information.

Q12889

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5 µg/mL", "IHCP-species-notes": "<p></p>" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

OVGP1 also known as oviductal glycoprotein or OGP is a glycoprotein with a molecular mass around 120 kDa. This protein is expressed mainly in the oviduct epithelium in mammals. It is secreted during the peri-ovulatory phase and associates with the zona pellucida and the oocyte. OGP products are studied extensively due to their role in reproductive biology especially concerning fertilization and early embryonic development.

Biological function summary

OVGP1 plays an important role in reproduction. It interacts with the zona pellucida and helps facilitate sperm binding and penetration enhancing fertilization potential. The protein is not part of a large complex but is known for modifying the environment in the oviduct to support fertility. It also maintains the stability and permeability of the oocyte and embryo matrix impacting early stages of embryo development.

Pathways

OVGP1 influences reproductive pathways that involve sperm-egg interaction and embryo transport. The glycoprotein acts along pathways connected to fertilization affecting the zona pellucida's structural and functional properties which are also influenced by proteins like ZP3 (zona pellucida glycoprotein 3). These pathways ensure that the conditions in the oviduct are optimal for successful conception and embryo support.

OVGP1 has been linked to infertility and reproductive challenges. Altered expression or dysfunction of this protein can affect fertility contributing to conditions like fallopian tube disorders and ectopic pregnancies. It might also interact with other proteins related to infertility such as inhibin affecting its pathways and mechanisms. Understanding these interactions provides insight into the treatment and management of reproductive health issues.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development.

See full target information OVGP1

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Molecular reproduction and development 92:e70049 PubMed40838423

2025

Three-Dimensional Magnetic Bioprinting Spheroids as an In Vitro Model to Study the Oviductal Physiology.

Applications

Unspecified application

Species

Unspecified reactive species

Patricia Kubo Fontes,Ana Beatriz Florencio da Silva,Ana Beatriz Dos Reis Bartoli,Thays Antunes,Arnaldo Rodrigues Dos Santos Júnior,Marcella Pecora Milazzotto

Journal of animal science and biotechnology 15:129 PubMed39358766

2024

Maternal stress and the early embryonic microenvironment: investigating long-term cortisol effects on bovine oviductal epithelial cells using air-liquid interface culture.

Applications

Unspecified application

Species

Unspecified reactive species

Fiona Wahl,Jianchao Huo,Shuaizhi Du,Jennifer Schoen,Shuai Chen

Histochemistry and cell biology 161:521-537 PubMed38530407

2024

Oxygen levels affect oviduct epithelium functions in air-liquid interface culture.

Applications

Unspecified application

Species

Unspecified reactive species

Jianchao Huo,Aleksandra Maria Mówińska,Ali Necmi Eren,Jennifer Schoen,Shuai Chen

Cytotechnology 74:531-538 PubMed36238264

2022

Long-term culture of feline oviduct epithelial cells on permeable filter supports.

Applications

Unspecified application

Species

Unspecified reactive species

Susanne Eder,Karin Müller,Shuai Chen,Jennifer Schoen

Journal of medical primatology 47:362-370 PubMed29971796

2018

Hormonal regulation of oviductal glycoprotein 1 (OVGP1; MUC9) in the rhesus macaque cervix.

Applications

Unspecified application

Species

Unspecified reactive species

Ov Daniel Slayden,Francis Kathryn E Friason,Kise Rosen Bond,Emily Cathleen Mishler

Theriogenology 80:862-9 PubMed23973051

2013

Long-term culture of primary porcine oviduct epithelial cells: validation of a comprehensive in vitro model for reproductive science.

Applications

Unspecified application

Species

Unspecified reactive species

Shuai Chen,Ralf Einspanier,Jennifer Schoen

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-OVGP1/OGP antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OVGP1/OGP antibody (AB118590)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Alternative Products

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Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (6)

Product promise