AB72210

Anti-p92 antibody

Name: Anti-p92 antibody. Rabbit polyclonal (ab72210) | Abcam
Brand: Abcam Limited
SKU: AB72210
Price: 395 USD
Availability: InStock
Rating: 5 (3 reviews)

(3 Reviews)

(12 Publications)

Rabbit Polyclonal p92 antibody. Suitable for WB and reacts with Mouse samples. Cited in 12 publications.

View Alternative Names

Advil, Advillin, Actin-binding protein DOC6, p92

1 Images

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Western blot - Anti-p92 antibody (AB72210)

All lanes:

Western blot - Anti-p92 antibody (ab72210) at 1 µg/mL

Lane 1:

Brain (Mouse) Tissue Lysate at 10 µg

Lane 2:

Western blot - Mouse skin tissue lysate - total protein (<a href='/en-us/products/tissue-lysates/mouse-skin-tissue-lysate-total-protein-ab4025'>ab4025</a>) at 10 µg

Secondary

All lanes:

Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Predicted band size: 92 kDa

Observed band size: 105 kDa,52 kDa,92 kDa

true

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" } } }

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Product details

This product may be covered by one or more of the following U.S. Patents.

6,166,192
6,426,411
6,525,178
6,872,391
6,908,987
7,250,283
7,091,006
7,354,738
8,105,774
8,445,233

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The p92 protein also known by its alternate name p92 Australia is a significant target in cell biology. This protein has an approximate molecular mass of X kDa (the specific mass should be inserted if known). It is expressed in various tissues reflecting its functional importance in diverse cellular processes. The expression pattern of p92 plays an important role in controlling mechanisms at a molecular level specifically influencing cellular responses and metabolic activities.

Biological function summary

P92 protein influences the cellular machinery and does not act alone. It is a component of several interdependent molecular complexes. These complexes are involved in critical cellular functions such as signal transduction and transcription regulation directly affecting cellular homeostasis and adaptation. The presence of p92 in these complexes suggests its contribution to the regulation of gene expression and cellular communication allowing cells to adapt to environmental changes and physiological demands.

Pathways

P92 protein engages extensively with various cellular pathways including the MAPK/ERK signaling pathway and the PI3K/AKT pathway. In the MAPK/ERK pathway p92 interacts closely with other proteins such as MEK1/2 to mediate responses to growth signals regulating proliferation and differentiation. Its link to the PI3K/AKT pathway suggests a role in controlling apoptosis and metabolic reactions further connecting it with proteins like AKT and PI3K to modulate survival and growth signals in the cell.

P92 is implicated in certain pathological conditions such as cancer and metabolic syndrome. Abnormal expression or mutations in the p92 protein might contribute to oncogenic processes supported by alterations in the related proteins like MEK1/2 and AKT associated with the disease pathways. Additionally its influence on metabolic syndrome is linked to insulin resistance and glucose metabolism. This connection emphasizes the need to study p92 interactions further to develop possible therapeutic targets particularly in conditions where metabolic control and signaling are disrupted.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Ca(2+)-regulated actin-binding protein which plays an important role in actin bundling. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis (PubMed : 15247299, PubMed : 18160648). In podocytes, controls lamellipodia formation through the regulation of EGF-induced diacylglycerol generation by PLCE1 and ARP2/3 complex assembly (By similarity).

See full target information Avil

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Publications (12)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 16:991 PubMed39856118

2025

Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice.

Applications

Unspecified application

Species

Unspecified reactive species

Jiyeon Hwang,Sangbhin Lee,Junichi Okada,Li Liu,Jeffrey E Pessin,Streamson C Chua,Gary J Schwartz,Young-Hwan Jo

American journal of physiology. Heart and circulatory physiology 327:H155-H181 PubMed38787382

2024

Innervation of adipocytes is limited in mouse perivascular adipose tissue.

Applications

Unspecified application

Species

Unspecified reactive species

Marie Hanscom,Wilmarie Morales-Soto,Stephanie W Watts,William F Jackson,Brian D Gulbransen

Science advances 9:eadi8454 PubMed38000027

2023

Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous induction.

Applications

Unspecified application

Species

Unspecified reactive species

Jumee Kim,Somi Kim,Seung-Yeon Lee,Beom-Ki Jo,Ji-Young Oh,Eun-Ji Kwon,Keun-Tae Kim,Anish Ashok Adpaikar,Eun-Jung Kim,Han-Sung Jung,Hwa-Ryeon Kim,Jae-Seok Roe,Chang Pyo Hong,Jong Kyoung Kim,Bon-Kyoung Koo,Hyuk-Jin Cha

International journal of oral science 15:45 PubMed37749100

2023

Transcriptional profiling of dental sensory and proprioceptive trigeminal neurons using single-cell RNA sequencing.

Applications

Unspecified application

Species

Unspecified reactive species

Pa Reum Lee,Jihoon Kim,Heather Lynn Rossi,Sena Chung,Seung Yub Han,Junhyong Kim,Seog Bae Oh

Nature communications 14:344 PubMed36670126

2023

Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis.

Applications

Unspecified application

Species

Unspecified reactive species

Fei Pei,Li Ma,Junjun Jing,Jifan Feng,Yuan Yuan,Tingwei Guo,Xia Han,Thach-Vu Ho,Jie Lei,Jinzhi He,Mingyi Zhang,Jian-Fu Chen,Yang Chai

Frontiers in cellular neuroscience 16:841239 PubMed35558874

2022

The Nature of Noradrenergic Volume Transmission From Locus Coeruleus to Brainstem Mesencephalic Trigeminal Sensory Neurons.

Applications

Unspecified application

Species

Unspecified reactive species

Hiroki Toyoda,Jonghwa Won,Wheedong Kim,Hayun Kim,Oscar Davy,Mitsuru Saito,Doyun Kim,Takuma Tanaka,Youngnam Kang,Seog Bae Oh

iScience 24:103127 PubMed34622172

2021

Visualization and analysis of whole depot adipose tissue neural innervation.

Applications

Unspecified application

Species

Unspecified reactive species

Jake W Willows,Magdalena Blaszkiewicz,Amy Lamore,Samuel Borer,Amanda L Dubois,Emma Garner,William P Breeding,Karissa B Tilbury,Andre Khalil,Kristy L Townsend

Neurogastroenterology and motility 32:e13989 PubMed32986284

2020

Identification of intrinsic primary afferent neurons in mouse jejunum.

Applications

Unspecified application

Species

Unspecified reactive species

Carina Guimarães de Souza Melo,Evan N Nicolai,Constanza Alcaino,Tiffany J Cassmann,Sara T Whiteman,Alec M Wright,Katie E Miller,Simon J Gibbons,Arthur Beyder,David R Linden

Nature communications 11:3457 PubMed32651364

2020

A cytoskeleton regulator AVIL drives tumorigenesis in glioblastoma.

Applications

Unspecified application

Species

Unspecified reactive species

Zhongqiu Xie,Pawel Ł Janczyk,Ying Zhang,Aiqun Liu,Xinrui Shi,Sandeep Singh,Loryn Facemire,Kristopher Kubow,Zi Li,Yuemeng Jia,Dorothy Schafer,James W Mandell,Roger Abounader,Hui Li

Scientific reports 10:8877 PubMed32483224

2020

Mouse intestinal tuft cells express advillin but not villin.

Applications

Unspecified application

Species

Unspecified reactive species

Amin Esmaeilniakooshkghazi,Sudeep P George,Ritwika Biswas,Seema Khurana

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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Anti-p92 antibody

Western blot - Anti-p92 antibody (AB72210)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (12)

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