Rabbit Polyclonal PABPC1L antibody. Suitable for WB, IHC-P and reacts with Rat, Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human PABPC1L aa 500 to C-terminus.
IgG
Rabbit
pH: 7.4
Preservative: 0.011% Proclin 300
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.219% PBS
Liquid
Polyclonal
WB | IHC-P | |
---|---|---|
Human | Tested | Tested |
Rat | Tested | Expected |
Species | Dilution info | Notes |
---|---|---|
Species Rat | Dilution info 0.2-2 µg/mL | Notes - |
Species Human | Dilution info 0.2-2 µg/mL | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 5-20 µg/mL | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Rat | Dilution info Use at an assay dependent concentration. | Notes - |
C20orf119, PABPC1L, Polyadenylate-binding protein 1-like
Rabbit Polyclonal PABPC1L antibody. Suitable for WB, IHC-P and reacts with Rat, Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human PABPC1L aa 500 to C-terminus.
IgG
Rabbit
pH: 7.4
Preservative: 0.011% Proclin 300
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.219% PBS
Liquid
Polyclonal
Affinity purification Protein A
ab233280 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
This supplementary information is collated from multiple sources and compiled automatically.
PABPC1L also known as cytoplasmic poly(A)-binding protein 1-like is a protein encoded by the PABPC1L gene. It weighs approximately 72 kDa. This protein binds to the poly(A) tail of mRNA molecules facilitating the regulation of mRNA stability and translation. PABPC1L shows expression in various tissues with notable expression in testis and oocytes where it functions during gametogenesis.
PABPC1L influences mRNA metabolic processes and is important during oocyte maturation and early embryogenesis. It acts as a regulator of mRNA decay and translation control most likely as part of larger ribonucleoprotein complexes. By connecting with other RNA-binding proteins PABPC1L helps modulate translational control during the transition from a quiescent oocyte to an activated embryo facilitating proper development stages.
PABPC1L participates in mRNA surveillance and translational control. It notably operates in pathways like the mRNA decay pathway where it works closely with other proteins including eukaryotic initiation factors. PABPC1L interacts with such factors to fine-tune the balance between mRNA translation and degradation impacting protein synthesis in embryonic cells.
PABPC1L has connections with reproductive and developmental conditions. Aberrant expression may link to impaired gamete formation and fertility issues. Its association with other RNA-binding proteins reinforces connections to reproductive disorders. Additionally PABPC1L's role in early embryonic development suggests potential links to embryogenesis disorders where proper mRNA regulation is critical.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
Formalin-fixed, paraffin-embedded human liver tissue stained for PABPC1L using ab233280 at 20 μg/ml in immunohistochemical analysis. DAB staining.
All lanes: Western blot - Anti-PABPC1L antibody (ab233280) at 2 µg/mL
All lanes: Rat liver lysate
All lanes: HRP-Linked Goat Anti-Rabbit IgG Polyclonal at 0.2 µg/mL
Predicted band size: 68 kDa
All lanes: Western blot - Anti-PABPC1L antibody (ab233280) at 2 µg/mL
All lanes: Recombinant human PABPC1L protein
Predicted band size: 68 kDa
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com