AB104162

Anti-PAF-R antibody

Name: Anti-PAF-R antibody (ab104162) | Abcam
Brand: Abcam Limited
SKU: AB104162
Price: 535 USD
Availability: InStock
Rating: 3 (1 reviews)

(1 Review)

(18 Publications)

Rabbit Polyclonal PAF-R antibody. Suitable for ICC, IP, Flow Cyt, WB and reacts with Human samples. Cited in 18 publications. Immunogen corresponding to Synthetic Peptide within Human PTAFR aa 1-50 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

PAFR, PTAFR, Platelet-activating factor receptor, PAF-R, PAFr

1 Images

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Western blot - Anti-PAF-R antibody (AB104162)

All lanes:

Western blot - Anti-PAF-R antibody (ab104162) at 1 µg/mL

Lane 1:

Molecular weight markers

Lane 2:

A549 membrane fraction at 30 µg

Secondary

All lanes:

Anti-rabbit IgG (HRP) conjugate at 1/10000 dilution

Predicted band size: 39 kDa

true

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

Flow Cyt, IP, WB, ICC

applications

Immunogen

Synthetic Peptide within Human PTAFR aa 1-50 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

P25105

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<a href='/en-us/products/primary-antibodies/rabbit-igg-polyclonal-isotype-control-chip-grade-ab171870'>ab171870</a> - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/200", "WB-species-notes": "" }, "Mouse": { "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 50% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Stable for 12 months at -20°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.

See full target information PTAFR

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Publications (18)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 16:1579551 PubMed40520162

2025

Respiratory virus-induced bacterial dysregulation in pediatric airway tissue and the dual actions of Echinacea in reducing complications.

Applications

Unspecified application

Species

Unspecified reactive species

Selvarani Vimalanathan,Mahfuza Sreya,Ranganayaki Nandanavanam,Roland Schoop,Giuseppe Gancitano,Saba Saberi,Anna Malikovskaia,James Hudson

Human genomics 18:139 PubMed39709510

2024

Identifying PTAFR as a hub gene in atherosclerosis: implications for NETosis and disease progression.

Applications

Unspecified application

Species

Unspecified reactive species

Chaowen Ye,Yunli Zhao,Wei Yu,Rongzhong Huang,Tianyang Hu

Lipids in health and disease 23:113 PubMed38643113

2024

Polar lipids modify Alzheimer's Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation.

Applications

Unspecified application

Species

Unspecified reactive species

Sakshi Hans,Janelle E Stanton,Ann Katrin Sauer,Katie Shiels,Sushanta Kumar Saha,Ronan Lordan,Alexandros Tsoupras,Ioannis Zabetakis,Andreas M Grabrucker

Journal of clinical medicine 12: PubMed38068409

2023

Upregulation of Platelet-Activating Factor Receptor Expression and Lyso-Platelet-Activating Factor Isoforms in Human Nasal Polyp Tissues.

Applications

Unspecified application

Species

Unspecified reactive species

Jordi Roca-Ferrer,Maria Pérez-González,Isam Alobid,Valeria Tubita,Mireya Fuentes,Marina Bantulà,Rosa Muñoz-Cano,Antonio Valero,Iñaki Izquierdo,Joaquim Mullol

Scientific reports 13:21637 PubMed38062077

2023

Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation.

Applications

Unspecified application

Species

Unspecified reactive species

Irismara Sousa Silva,Aline D Almeida,Antônio C M Lima Filho,Weslley Fernandes-Braga,Ayslan Barra,Hortência M C Oliveira,Geovanni D Cassali,Luciano S A Capettini,Gustavo B Menezes,Jacqueline I Alvarez-Leite,Maria F Leite,André Klein

iScience 26:105923 PubMed36685035

2023

Streptococcus pneumoniae promotes lung cancer development and progression.

Applications

Unspecified application

Species

Unspecified reactive species

Ning Li,Huifen Zhou,Van K Holden,Janaki Deepak,Pushpa Dhilipkannah,Nevins W Todd,Sanford A Stass,Feng Jiang

EBioMedicine 80:104063 PubMed35598440

2022

Underground railway particulate matter and susceptibility to pneumococcal infection.

Applications

Unspecified application

Species

Unspecified reactive species

Lisa Miyashita,Rebecca Shears,Gary Foley,Sean Semple,Aras Kadioglu,Jonathan Grigg

Veterinary microbiology 255:109017 PubMed33639390

2021

Bovine respiratory coronavirus enhances bacterial adherence by upregulating expression of cellular receptors on bovine respiratory epithelial cells.

Applications

Unspecified application

Species

Unspecified reactive species

Watcharapong Fahkrajang,Putu Eka Sudaryatma,Hirohisa Mekata,Saori Hamabe,Akatsuki Saito,Tamaki Okabayashi

Cell death & disease 12:23 PubMed33414461

2021

Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.

Applications

Unspecified application

Species

Unspecified reactive species

Jin Yang,Lu-Lu Cao,Xi-Peng Wang,Wei Guo,Ruo-Bing Guo,Yu-Qin Sun,Teng-Fei Xue,Zhen-Yu Cai,Juan Ji,Hong Cheng,Xiu-Lan Sun

Experimental and therapeutic medicine 21:28 PubMed33262814

2020

Shikonin reduces hepatic fibrosis by inducing apoptosis and inhibiting autophagy via the platelet-activating factor-mitogen-activated protein kinase axis.

Applications

Unspecified application

Species

Unspecified reactive species

Min Song,Heng Zhang,Zhitao Chen,Jing Yang,Jie Li,Sue Shao,Jing Liu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PAF-R antibody

Western blot - Anti-PAF-R antibody (AB104162)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (18)

Complementary Products

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise