Rabbit Polyclonal PAI1 antibody. Suitable for WB and reacts with Rat samples. Cited in 9 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Rat Serpine1.
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- Mediators of inflammation 2021:55993642021p300/Sp1-Mediated High Expression of p16 Promotes Endothelial Progenitor Cell Senescence Leading to the Occurrence of Chronic Obstructive Pulmonary Disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZhihui He,Huaihuai Peng,Min Gao,Guibin Liang,Menghao Zeng,Xuefeng ZhangPubMed 34456628
- Brazilian journal of medical and biological resear 53:e88262020Decreased expression of microRNA-17 in hippocampal tissues and blood from mice with depression up-regulates the expression of PAI-1 mRNA and protein.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMin Lv et. al.PubMed 32901686
- Endocrinology 159:2621-26392018Changes in Corticotrope Gene Expression Upon Increased Expression of Peptidylglycine α-Amidating Monooxygenase.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRichard E Mains,Crysten Blaby-Haas,Bruce A Rheaume,Betty A EipperPubMed 29788427
- Experimental and therapeutic medicine 15:5125-51322018MicroRNA-30b protects myocardial cell function in patients with acute myocardial ischemia by targeting plasminogen activator inhibitor-1.Applications:Unspecified applicationReactive species:Unspecified reactive speciesBin Li et. al.PubMed 29805539
- FASEB journal : official publication of the Federa 29:4956-672015Extracellular matrix-induced Hic-5 expression in glomerular mesangial cells leads to a prosclerotic phenotype independent of TGF-β.Applications:Unspecified applicationReactive species:Unspecified reactive speciesNick Hornigold et. al.PubMed 26405299
- PloS one 8:e674702013NGF upregulates the plasminogen activation inhibitor-1 in neurons via the calcineurin/NFAT pathway and the Down syndrome-related proteins DYRK1A and RCAN1 attenuate this effect.Applications:WBReactive species:Unspecified reactive speciesGeorgios C Stefos,Ulf Soppa,Mara Dierssen,Walter BeckerPubMed 23825664
- FEBS letters 586:3317-232012N-terminal tyrosine phosphorylation of caveolin-2 negates anti-proliferative effect of transforming growth factor beta in endothelial cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesBritain Abel et. al.PubMed 22819829
- The Journal of endocrinology 200:207-212008Vitamin D reduces the expression of collagen and key profibrotic factors by inducing an antifibrotic phenotype in mesenchymal multipotent cells.
- The Journal of endocrinology 196:235-492008Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJorge N Artaza,Rajan Singh,Monica G Ferrini,Melissa Braga,James Tsao,Nestor F Gonzalez-CadavidPubMed 18252947
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 6.5
Preservative: 0.1% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Full Length Protein corresponding to Rat Serpine1. Database link P20961
Reactivity data
Select an application| WB | |
|---|---|
| Rat | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info 1/1000 | Notes - |
Associated Products
Select an associated product type
7 products for Alternative Product
Target data
Function
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence (By similarity). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity).
Alternative names
Pai1, Planh1, Serpine1, Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1
Recommended products
Rabbit Polyclonal PAI1 antibody. Suitable for WB and reacts with Rat samples. Cited in 9 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Rat Serpine1.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 6.5
Preservative: 0.1% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Full Length Protein corresponding to Rat Serpine1. Database link P20961
- Purification technique
- Affinity purification Protein A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
Western blot - Anti-PAI1 antibody (ab7205)
Rat PAI1 detected by Western blot on Day 3 in a glomerular nephritis model.
All lanes: Western blot - Anti-PAI1 antibody (ab7205) at 1/1000 dilution
Predicted band size: 45 kDa
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