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Rabbit Polyclonal PAIP2 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human, Mouse samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human PAIP2.

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Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PAIP2 antibody (AB237803), expandable thumbnail
  • Immunocytochemistry/ Immunofluorescence - Anti-PAIP2 antibody (AB237803), expandable thumbnail
  • Western blot - Anti-PAIP2 antibody (AB237803), expandable thumbnail

Key facts

Isotype
IgG
Host species
Rabbit
Storage buffer

pH: 7.4
Preservative: 0.03% Proclin 300
Constituents: PBS, 50% Glycerol (glycerin, glycerine)

Form
Liquid
Clonality
Polyclonal

Immunogen

  • Recombinant Full Length Protein corresponding to Human PAIP2. Database link Q9BPZ3

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WBIHC-PICC/IF
Human
Tested
Tested
Tested
Mouse
Tested
Expected
Expected
Rat
Predicted
Predicted
Predicted
Chicken
Predicted
Predicted
Predicted
Cow
Predicted
Predicted
Predicted
Orangutan
Predicted
Predicted
Predicted

Tested
Tested

Species
Human
Dilution info
1/500.00000 - 1/5000.00000
Notes

-

Species
Mouse
Dilution info
1/500.00000 - 1/5000.00000
Notes

-

Predicted
Predicted

Species
Rat, Chicken, Cow, Orangutan
Dilution info
-
Notes

-

Tested
Tested

Species
Human
Dilution info
1/20.00000 - 1/200.00000
Notes

-

Expected
Expected

Species
Mouse
Dilution info
Use at an assay dependent concentration.
Notes

-

Predicted
Predicted

Species
Rat, Chicken, Cow, Orangutan
Dilution info
-
Notes

-

Tested
Tested

Species
Human
Dilution info
1/50.00000 - 1/200.00000
Notes

-

Expected
Expected

Species
Mouse
Dilution info
Use at an assay dependent concentration.
Notes

-

Predicted
Predicted

Species
Rat, Chicken, Cow, Orangutan
Dilution info
-
Notes

-

Target data

Function

Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.

Alternative names

Recommended products

Rabbit Polyclonal PAIP2 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human, Mouse samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human PAIP2.

Key facts

Isotype
IgG
Form
Liquid
Clonality
Polyclonal
Immunogen
  • Recombinant Full Length Protein corresponding to Human PAIP2. Database link Q9BPZ3
Purification technique
Affinity purification Protein G
Concentration
Loading...
Purification notes

Purity greater than 95%.

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

3 product images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PAIP2 antibody (ab237803), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PAIP2 antibody (ab237803)

    Paraffin-embedded human lung tissue stained for PAIP2 using ab237803 at 1/100 dilution in immunohistochemical analysis.

  • Immunocytochemistry/ Immunofluorescence - Anti-PAIP2 antibody (ab237803), expandable thumbnail

    Immunocytochemistry/ Immunofluorescence - Anti-PAIP2 antibody (ab237803)

    HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for PAIP2 (green) using ab237803 at 1/100 dilution in ICC/IF, followed by Alexa Fluor® 488-congugated Goat Anti-Rabbit IgG (H+L) secondary antibody.

  • Western blot - Anti-PAIP2 antibody (ab237803), expandable thumbnail

    Western blot - Anti-PAIP2 antibody (ab237803)

    All lanes: Western blot - Anti-PAIP2 antibody (ab237803) at 1/500 dilution

    Lane 1: HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate

    Lane 2: Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate

    Lane 3: SH-SY5Y (human neuroblastoma cell line from bone marrow) whole cell lysate

    Lane 4: HEK-293 (human epithelial cell line from embryonic kidney) whole cell lysate

    Lane 5: Mouse lung tissue lysate

    Lane 6: Mouse liver tissue lysate

    Lane 7: Mouse kidney tissue lysate

    Lane 8: Mouse brain tissue lysate

    Secondary

    All lanes: Goat polyclonal to rabbit IgG at 1/50000 dilution

    Predicted band size: 15 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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