Rabbit Polyclonal TEAD4 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 16 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TEAD4 aa 1-250.
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- Theranostics 13:4182-41962023Endothelial TAZ inhibits capillarization of liver sinusoidal endothelium and damage-induced liver fibrosis nitric oxide production.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJun-Ha Hwang,Woong Heo,Jung Il Park,Kyung Min Kim,Ho Taek Oh,Gi Don Yoo,Jeekeon Park,Somin Shin,Youjin Do,Mi Gyeong Jeong,Eun Sook Hwang,Jeong-Ho HongPubMed 37554269
- The Journal of clinical investigation 132:2022RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPeng Deng,Zining Wang,Jinghong Chen,Shini Liu,Xiaosai Yao,Shaoyan Liu,Lizhen Liu,Zhaoliang Yu,Yulin Huang,Zhongtang Xiong,Rong Xiao,Jiuping Gao,Weiting Liang,Jieping Chen,Hui Liu,Jing Han Hong,Jason Yongsheng Chan,Peiyong Guan,Jianfeng Chen,Yali Wang,Jiaxin Yin,Jundong Li,Min Zheng,Chao Zhang,Penghui Zhou,Tiebang Kang,Bin Tean Teh,Qiang Yu,Zhixiang Zuo,Qingping Jiang,Jihong Liu,Ying Xiong,Xiaojun Xia,Jing TanPubMed 36201246
- Developmental cell 57:2450-2468.e72022Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRasmani Hazra,Lily Brine,Libia Garcia,Brian Benz,Napon Chirathivat,Michael M Shen,John Erby Wilkinson,Scott K Lyons,David L SpectorPubMed 36347239
- Developmental cell 57:212-227.e82022YAP1 and PRDM14 converge to promote cell survival and tumorigenesis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMiju Kim,Seav Huong Ly,Yingtian Xie,Gina N Duronio,Dane Ford-Roshon,Justin H Hwang,Rita Sulahian,Jonathan P Rennhack,Jonathan So,Ole Gjoerup,Jessica A Talamas,Maximilien Grandclaudon,Henry W Long,John G Doench,Nilay S Sethi,Marios Giannakis,William C HahnPubMed 34990589
- APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 129:729-7422021High YAP and TEAD4 immunolabelings are associated with poor prognosis in patients with gallbladder cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJoo Young Kim,You-Na Sung,Seung-Mo HongPubMed 34779030
- Acta pharmacologica Sinica 42:1847-18592021Targeting the ILK/YAP axis by LFG-500 blocks epithelial-mesenchymal transition and metastasis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesCheng-Lin Li,Juan Li,Shu-Yuan Gong,Meng Huang,Rui Li,Gui-Xiang Xiong,Fan Wang,Qiu-Ming Zou,Qi Qi,Xiao-Xing YinPubMed 33879841
- Journal of cancer research and clinical oncology 147:373-3912020The clinical relevance of the Hippo pathway in pancreatic ductal adenocarcinoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRichard Drexler,Mirco Küchler,Kim C Wagner,Tim Reese,Bernd Feyerabend,Moritz Kleine,Karl J OldhaferPubMed 33098447
- Nature 586:612-6172020A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShantha K Mahadevaiah et. al.PubMed 32814901
- European review for medical and pharmacological sciences 23:755-7632019Activated YAP causes renal damage of type 2 diabetic nephropathy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesR Ma,J-M Ren,P Li,Y-J Zhou,M-K Zhou,Z Hu,X-Y XiaoPubMed 30720184
- Nature communications 10:4212019TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJun-Ha Hwang,A Rum Kim,Kyung Min Kim,Jung Il Park,Ho Taek Oh,Sung A Moon,Mi Ran Byun,Hana Jeong,Hyo Kyung Kim,Michael B Yaffe,Eun Sook Hwang,Jeong-Ho HongPubMed 30679431
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 20% Glycerol (glycerin, glycerine), 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human TEAD4 aa 1-250. The exact immunogen used to generate this antibody is proprietary information. Database link Q15561
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Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Tested |
| Mouse | Predicted | Predicted |
| Pig | Predicted | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500 - 1/3000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Pig | Dilution info - | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/100 - 1/500 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Pig | Dilution info - | Notes - |
Associated Products
Select an associated product type
2 products for Alternative Product
Target data
Function
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.
Alternative names
RTEF1, TCF13L1, TEF3, TEAD4, Transcriptional enhancer factor TEF-3, TEA domain family member 4, Transcription factor 13-like 1, Transcription factor RTEF-1, TEAD-4
Recommended products
Rabbit Polyclonal TEAD4 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 16 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TEAD4 aa 1-250.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 20% Glycerol (glycerin, glycerine), 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human TEAD4 aa 1-250. The exact immunogen used to generate this antibody is proprietary information. Database link Q15561
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
3 product images
Western blot - Anti-PAN TEAD antibody (ab97460)
10% SDS PAGE
All lanes: Western blot - Anti-PAN TEAD antibody (ab97460) at 1/1000 dilution
All lanes: HepG2 cell lysate at 30 µg
Predicted band size: 48 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PAN TEAD antibody (ab97460)
ab97460, at 1/500 dilution, staining PAN TEAD in a paraffin-embedded SW480 (human) xenograft by Immunohistochemical analysis
Western blot - Anti-PAN TEAD antibody (ab97460)
Blocking and diluting buffer: 5% NFDM /TBST
All lanes: Western blot - Anti-PAN TEAD antibody (ab97460) at 1/1000 dilution
Lane 1: TEAD1 Human Recombinant Protein at 20 µg
Lane 2: TEAD2 Human Recombinant Protein at 20 µg
Lane 3: TEAD3 Human Recombinant Protein at 20 µg
Lane 4: TEAD4 Human Recombinant Protein at 20 µg
SecondaryAll lanes: Western blot - Goat Anti-Rabbit IgG H&L (HRP) (Goat Anti-Rabbit IgG H&L (HRP) ab97051) at 1/20000 dilution
Exposure time: 180s
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