Sheep Polyclonal AMYP antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Native Full Length Protein corresponding to Human Pancreatic alpha-amylase.
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- Frontiers in cell and developmental biology 9:7051822021ATXN10 Is Required for Embryonic Heart Development and Maintenance of Epithelial Cell Phenotypes in the Adult Kidney and Pancreas.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMelissa R Bentley-Ford,Reagan S Andersen,Mandy J Croyle,Courtney J Haycraft,Kelsey R Clearman,Jeremy B Foote,Jeremy F Reiter,Bradley K YoderPubMed 34970537
- Journal of applied physiology (Bethesda, Md. : 198 125:97-1062018Development of a polarized pancreatic ductular cell epithelium for physiological studies.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYunxia O'Malley et. al.PubMed 29517421
Key facts
- Isotype
- IgG
- Host species
- Sheep
- Storage buffer
Preservative: 0.09% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Native Full Length Protein corresponding to Human Pancreatic alpha-amylase. Database link P04746
Reactivity data
Select an application| IHC-P | |
|---|---|
| Human | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 2.5 µg/mL | Notes Perform heat-mediated antigen retrieval before commencing with IHC staining protocol. |
Associated Products
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2 products for Alternative Product
Alternative names
Pancreatic alpha-amylase, PA, AMY2A
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Sheep Polyclonal AMYP antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Native Full Length Protein corresponding to Human Pancreatic alpha-amylase.
Key facts
- Isotype
- IgG
- Host species
- Sheep
- Storage buffer
Preservative: 0.09% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Native Full Length Protein corresponding to Human Pancreatic alpha-amylase. Database link P04746
- Purification technique
- Affinity purification Protein G
- Specificity
This antibody recongizes native AMY2A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
Pancreatic alpha amylase also known as AMY2A is an enzyme responsible for catalyzing the hydrolysis of starch into sugars. This enzyme is an important amylase protein with a molecular mass of approximately 56 kDa. It is abundantly expressed in the pancreas of mammals playing a significant role in the digestive process. The product of its activity maltose contributes to carbohydrate digestion allowing for energy production in the body.
- Biological function summary
Pancreatic alpha amylase assists in the breakdown of large polysaccharides into smaller maltose units. This enzyme can act independently and does not require a complex to function effectively. It carries out its activity primarily in the small intestine where it continues the digestive process initiated by salivary alpha amylase. This amylase protein ensures that starches consumed in the diet are converted into forms absorbable by the body contributing to overall metabolism.
- Pathways
Pancreatic alpha amylase is a critical enzyme in the digestive pathway especially in the carbohydrate digestion and absorption pathway. Its activity complements that of other amylase enzymes including salivary alpha amylase to ensure efficient starch breakdown. Additionally pancreatic alpha amylase works in conjunction with proteins like glucose transporters which facilitate the entry of glucose into cells after starch breakdown.
- Associated diseases and disorders
The activity of pancreatic alpha amylase often links to conditions such as pancreatitis and type 2 diabetes. Elevated levels of this enzyme in the bloodstream can indicate acute pancreatitis highlighting its significance in diagnosing this disorder. In the context of diabetes altered pancreatic amylase activity can affect glucose metabolism. The enzyme's association with glucose-regulating proteins such as insulin makes it a focal point in understanding diabetic pathophysiology.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Pancreatic alpha amylase antibody (ab189341)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pancreas tissue, labeling AMY2A using ab189341 at 2.5 μg/ml.
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