AB79517

Anti-PAQR5 antibody

Name: Anti-PAQR5 antibody (ab79517) | Abcam
Brand: Abcam Limited
SKU: AB79517
Price: 535 USD
Availability: InStock
Rating: 5 (2 reviews)

(2 Reviews)

(11 Publications)

Rabbit Polyclonal PAQR5 antibody. Suitable for WB and reacts with Human samples. Cited in 11 publications. Immunogen corresponding to Synthetic Peptide within Human PAQR5.

View Alternative Names

MPRG, PAQR5, Membrane progestin receptor gamma, mPR gamma, Membrane progesterone P4 receptor gamma, Membrane progesterone receptor gamma, Progesterone and adipoQ receptor family member 5, Progestin and adipoQ receptor family member 5, Progestin and adipoQ receptor family member V

2 Images

AbReview45444****

Western blot - Anti-PAQR5 antibody (AB79517)

All lanes:

Western blot - Anti-PAQR5 antibody (ab79517) at 500 µg

Lane 1:

HUVEC cell lysate (positive control) at 40 µg

Lanes 2 - 4:

Non-pregnant ovine caruncle tissue lysate at 40 µg

Lanes 5 - 7:

Day 30 of gestation ovine caruncle tissue lysate at 40 µg

Secondary

All lanes:

HRP-conjugated goat anti-rabbit IgG monoclonal at 1/5000 dilution

Predicted band size: 38 kDa

Observed band size: 42 kDa,52 kDa

true

This image is courtesy of an anonymous Abreview

Unknown

Western blot - Anti-PAQR5 antibody (AB79517)

All lanes:

Western blot - Anti-PAQR5 antibody (ab79517) at 1/500 dilution

Lane 1:

Extracts from HUVEC cells at 25 µg

Lane 2:

Extracts from HUVEC cells at 25 µg with mmunizing peptide

Predicted band size: 38 kDa

Observed band size: 38 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human PAQR5. The exact immunogen used to generate this antibody is proprietary information.

Q9NXK6

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed : 23763432). Seems to act through a G(i) mediated pathway (PubMed : 23763432). May be involved in oocyte maturation (PubMed : 12601167).

See full target information PAQR5

style

left-column

Publications (11)

Recent publications for all applications. Explore the full list and refine your search

Cancers 15: PubMed37894441

2023

New Insights on the Progesterone (P4) and PGRMC1/NENF Complex Interactions in Colorectal Cancer Progression.

Applications

Unspecified application

Species

Unspecified reactive species

Joanna Kamińska,Olga Martyna Koper-Lenkiewicz,Donata Ponikwicka-Tyszko,Weronika Lebiedzińska,Ewelina Palak,Maria Sztachelska,Piotr Bernaczyk,Justyna Dorf,Katarzyna Guzińska-Ustymowicz,Konrad Zaręba,Sławomir Wołczyński,Nafis Ahmed Rahman,Violetta Dymicka-Piekarska

Scientific reports 13:12871 PubMed37553369

2023

Decreased renal expression of PAQR5 is associated with the absence of a nephroprotective effect of progesterone in a rat UUO model.

Applications

Unspecified application

Species

Unspecified reactive species

P A Abramicheva,D S Semenovich,L D Zorova,I B Pevzner,I A Sokolov,V A Popkov,E P Kazakov,D B Zorov,E Y Plotnikov

Journal of clinical medicine 11: PubMed35956024

2022

Functional Implications of Estrogen and Progesterone Receptors Expression in Adenomyosis, Potential Targets for Endocrinological Therapy.

Applications

Unspecified application

Species

Unspecified reactive species

Maria Sztachelska,Donata Ponikwicka-Tyszko,Lydia Martínez-Rodrigo,Piotr Bernaczyk,Ewelina Palak,Weronika Półchłopek,Tomasz Bielawski,Sławomir Wołczyński

Biochemistry. Biokhimiia 86:1446-1460 PubMed34906046

2021

Cytotoxic Effects of the Selective Ligands of Membrane Progesterone Receptors in Human Pancreatic Adenocarcinoma Cells BxPC3.

Applications

Unspecified application

Species

Unspecified reactive species

Alexey I Goncharov,Inna S Levina,Viktoriia L Shliapina,Ivan A Morozov,Petr M Rubtsov,Igor V Zavarzin,Olga V Smirnova,Tatiana A Shchelkunova

Cancers 12: PubMed33158280

2020

Mifepristone Treatment Promotes Testicular Leydig Cell Tumor Progression in Transgenic Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Donata Ponikwicka-Tyszko,Marcin Chrusciel,Kamila Pulawska,Piotr Bernaczyk,Maria Sztachelska,Peilan Guo,Xiangdong Li,Jorma Toppari,Ilpo T Huhtaniemi,Slawomir Wołczyński,Nafis A Rahman

EBioMedicine 47:170-183 PubMed31466918

2019

Molecular mechanisms underlying mifepristone's agonistic action on ovarian cancer progression.

Applications

Unspecified application

Species

Unspecified reactive species

Donata Ponikwicka-Tyszko,Marcin Chrusciel,Joanna Stelmaszewska,Piotr Bernaczyk,Paulina Chrusciel,Maria Sztachelska,Mika Scheinin,Mariusz Bidzinski,Jacek Szamatowicz,Ilpo T Huhtaniemi,Slawomir Wolczynski,Nafis A Rahman

Biochemical pharmacology 154:118-126 PubMed29684377

2018

Biphasic modulation of cAMP levels by the contraceptive nomegestrol acetate. Impact on P-glycoprotein expression and activity in hepatic cells.

Applications

Species

Unspecified reactive species

Guillermo Nicolás Tocchetti,Camila Juliana Domínguez,Felipe Zecchinati,Maite Rocío Arana,María Laura Ruiz,Silvina Stella Maris Villanueva,Johanna Weiss,Aldo Domingo Mottino,Juan Pablo Rigalli

PloS one 11:e0165197 PubMed27814376

2016

Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Sarah L Roche,Alice C Wyse-Jackson,Violeta Gómez-Vicente,Pedro Lax,Ana M Ruiz-Lopez,Ashleigh M Byrne,Nicolás Cuenca,Thomas G Cotter

Journal of neurochemistry 136:63-77 PubMed26447367

2015

Progesterone receptor signalling in retinal photoreceptor neuroprotection.

Applications

Unspecified application

Species

Unspecified reactive species

Alice C Wyse Jackson,Sarah L Roche,Ashleigh M Byrne,Ana M Ruiz-Lopez,Thomas G Cotter

Reproduction (Cambridge, England) 150:43-52 PubMed25861798

2015

Human chorionic gonadotropin increases serum progesterone, number of corpora lutea and angiogenic factors in pregnant sheep.

Applications

Unspecified application

Species

Unspecified reactive species

Megan P T Coleson,Nicole S Sanchez,Amanda K Ashley,Timothy T Ross,Ryan L Ashley

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PAQR5 antibody

Western blot - Anti-PAQR5 antibody (AB79517)

Western blot - Anti-PAQR5 antibody (AB79517)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (11)

Alternative Products

Primary Antibodies

Complementary Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise