JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB6022

Anti-PAR6 antibody

Be the first to review this product! Submit a review

|

(2 Publications)

Goat Polyclonal PAR6 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human PARD6A aa 300 to C-terminus.

View Alternative Names

PAR6A, PARD6A, Partitioning defective 6 homolog alpha, PAR-6, PAR-6 alpha, PAR-6A, PAR6C, Tax interaction protein 40, TIP-40

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PAR6 antibody (AB6022)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PAR6 antibody (AB6022)

ab6022 (10ug/ml) staining human PAR6 in human pancreas by immunohistochemistry using paraffin embedded tissue. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. ab6022 shows strong cytoplasmic staining in rare cells of intralobular ducts.

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human PARD6A aa 300 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9NPB6

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-10 µg/mL", "IHCP-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Storage buffer
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed : 10873802). Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization (PubMed : 20719959).
See full target information PARD6A
style
left-column

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 21: PubMed31947656

2020

Enteropathogenic (EPEC) Recruitment of PAR Polarity Protein Atypical PKCζ to Pedestals and Cell-Cell Contacts Precedes Disruption of Tight Junctions in Intestinal Epithelial Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Rocio Tapia,Sarah E Kralicek,Gail A Hecht

Developmental cell 19:114-25 PubMed20643355

2010

Epicardial spindle orientation controls cell entry into the myocardium.

Applications

IHC-P

Species

Mouse

Mingfu Wu,Christopher L Smith,James A Hall,Ivy Lee,Kate Luby-Phelps,Michelle D Tallquist
View all publications
style
left-column
style
left-column
style
right-column

Alternative Products

Primary Antibodies

AB180159

Anti-PAR6 antibody [EPR12378] - N-terminal

RabMAb|Recombinant

Western blot - Anti-PAR6 antibody [EPR12378] - N-terminal (AB180159)

  • 0
  • 0

Complementary Products

Primary Antibodies

AB4069

Anti-Ezrin antibody [3C12]

BOND RX™ Validated|KO Validated

Flow Cytometry (Intracellular) - Anti-Ezrin antibody [3C12] (AB4069)

  • 3
  • 8
Primary Antibodies

AB32078

Anti-Src (phospho Y529) antibody [Y232]

20ul selling size|RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-Src (phospho Y529) antibody [Y232] (AB32078)

  • 5
  • 2
Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

  • 5
  • 15
Primary Antibodies

AB18207

Anti-beta III Tubulin antibody - Neuronal Marker

BOND RX™ Validated|Lab Essentials|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-beta III Tubulin antibody - Neuronal Marker (AB18207)

  • 5
  • 67

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com