Anti-Parotid secretory protein antibody
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(2 Publications)
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Immunocytochemistry/ Immunofluorescence - Anti-Parotid secretory protein antibody (AB121028)
Immunocytochemistry/immunofluorescence analysis of mouse submanidbular gland cells labelling parotid secretory protein with ab121028 at 4 μg/mL (blue). Cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100. Cells were counterstained with Ecad at 1/200 dilution (red). Nuclear DNA was labelled with DAPI (green).
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Biological function summary
The protein influences immune defense in salivary secretions. PSP is part of salivary innate immune responses and works alongside other salivary proteins for maintaining oral health. This protein contributes to the barrier function against bacteria and viruses inside the mouth. PSP is capable of agglutination of microbes making their removal by saliva more efficient.
Pathways
PSP is extensively involved in the immune defense pathways of the oral cavity and initial gastrointestinal tract. In these pathways PSP functions within networks including proteins such as mucins and histatins which collectively contribute to oral homeostasis and microbial balance. PSP’s ability to bind bacteria supports its role in these pathways by enhancing the prevention of infection and inflammation.
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Publications (2)
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iScience 26:106660 PubMed37168562
2023
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Unspecified application
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Frontiers in physiology 13:884166 PubMed35574458
2022
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Unspecified application
Species
Unspecified reactive species
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